多药耐药株，属于具有头孢曲松耐药性和对阿奇霉素中介耐药性的国际传播的日本 FC428 克隆株，爱尔兰，2018 年 8 月。
Multidrug-resistant isolate, belonging to the internationally spreading Japanese FC428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, Ireland, August 2018.
机构信息
WHO Collaborating Centre for Gonorrhoea and other Sexually Transmitted Infections, Swedish Reference Laboratory for Sexually Transmitted Infections, Department of Laboratory Medicine, Clinical Microbiology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Department of Clinical Microbiology, University of Dublin, Trinity College, St. James's Hospital, Dublin, Ireland.
出版信息
Euro Surveill. 2018 Nov;23(47). doi: 10.2807/1560-7917.ES.2018.23.47.1800617.
We describe a multidrug-resistant urethritis case with ceftriaxone resistance and azithromycin intermediate resistance in a heterosexual man in Ireland, August 2018. Whole-genome sequencing showed that the isolate IR72 belongs to the internationally spreading multidrug-resistant ceftriaxone-resistant FC428 clade, initially described in Japan in 2015. IR72 was assigned MSLT ST1903, NG-MAST ST17842 and NG-STAR type 1133, including the ceftriaxone resistance-mediating 60.001. Global awareness of spreading ceftriaxone-resistant gonococcal strains that threaten recommended dual therapies is essential.
我们描述了 2018 年 8 月在爱尔兰一名异性恋男性中出现的对头孢曲松耐药和阿奇霉素中介耐药的多重耐药性尿道炎病例。全基因组测序显示，分离株 IR72 属于国际传播的多重耐药性头孢曲松耐药 FC428 分支，最初于 2015 年在日本描述。IR72 被分配 MSLT ST1903、NG-MAST ST17842 和 NG-STAR 型 1133，包括介导头孢曲松耐药的 60.001。必须提高对威胁推荐的双重疗法的传播的头孢曲松耐药淋病菌株的全球认识。
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