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1
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2
Unusual symptoms and syndromes in multiple sclerosis.多发性硬化症中的异常症状和综合征
Continuum (Minneap Minn). 2013 Aug;19(4 Multiple Sclerosis):992-1006. doi: 10.1212/01.CON.0000433287.30715.07.
3
Teaching NeuroImage: Inverted V sign in subacute combined degeneration of spinal cord.教学神经影像学:脊髓亚急性联合变性中的倒V征
Neurology. 2009 Jan 6;72(1):e4. doi: 10.1212/01.wnl.0000338663.59433.9c.
4
Comparison of clinical and electrodiagnostic features in B12 deficiency neurological syndromes with and without antiparietal cell antibodies.伴有和不伴有抗壁细胞抗体的维生素B12缺乏神经综合征的临床和电诊断特征比较
Postgrad Med J. 2007 Feb;83(976):124-7. doi: 10.1136/pgmj.2006.048132.
5
[A case of multiple sclerosis with bilateral useless hand syndrome as a main clinical feature].以双侧失用手综合征为主要临床特征的多发性硬化症病例
Rinsho Shinkeigaku. 2005 Mar;45(3):211-5.
6
[Acute posterior cord lesions in multiple sclerosis. An MRI study of the clinical course in 20 cases].[多发性硬化症中的急性后索病变。20例临床病程的MRI研究]
Rev Neurol (Paris). 2000 Dec;156(12):1126-35.
7
MR findings in subacute combined degeneration of the spinal cord: a case of reversible cervical myelopathy.脊髓亚急性联合变性的磁共振成像表现:一例可逆性颈髓病病例
AJR Am J Roentgenol. 2000 Mar;174(3):863-5. doi: 10.2214/ajr.174.3.1740863.
8
[Left hand clumsiness due to disturbance of kinesthesia after damage to the dorsal column of the high cervical cord].[高颈髓后索损伤后因本体感觉障碍导致左手笨拙]
Rinsho Shinkeigaku. 1997 Apr;37(4):319-25.
9
Neurological complications of acquired cobalamin deficiency: clinical aspects.获得性钴胺素缺乏的神经系统并发症:临床方面
Baillieres Clin Haematol. 1995 Sep;8(3):657-78. doi: 10.1016/s0950-3536(05)80225-2.
10
Midcervical central cord syndrome: numb and clumsy hands due to midline cervical disc protrusion at the C3-4 intervertebral level.颈中部中央脊髓综合征:由于C3 - 4椎间水平的中线颈椎间盘突出导致手部麻木和笨拙。
J Neurol Neurosurg Psychiatry. 1995 May;58(5):607-13. doi: 10.1136/jnnp.58.5.607.

急性双侧失用手综合征:维生素B12缺乏症的一种罕见表现形式。

Acute bilateral useless hand syndrome: a rare presenting manifestation of vitamin B12 deficiency.

作者信息

Biyani Sumant, Jha Sneh Kumar, Pandey Suchit, Shukla Rakesh

机构信息

Department of Neurology, King George's Medical University, Lucknow, Uttar Pradesh, India.

出版信息

BMJ Case Rep. 2015 Oct 16;2015:bcr2015210067. doi: 10.1136/bcr-2015-210067.

DOI:10.1136/bcr-2015-210067
PMID:26475874
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4612725/
Abstract

We report a case of bilateral useless hand syndrome, a rare presenting manifestation of vitamin B12 deficiency. A 38-year-old man, a strict vegetarian and a teacher by occupation, presented with acute onset clumsiness of both hands while performing fine movements. Detailed history-taking, examination of the patient and relevant investigations (complete blood count, serum vitamin B12 and MRI of the cervical spinal cord) were carried out. Laboratory analysis was suggestive of vitamin B12 deficiency and MRI demonstrated a lesion involving the posterior columns of the cervical cord. The patient was diagnosed as a case of non-compressive cervical myelopathy predominantly involving the posterior column due to vitamin B12 deficiency. Acute bilateral useless hand syndrome can be a rare presenting feature of vitamin B12 deficiency.

摘要

我们报告一例双侧无功能手综合征,这是维生素B12缺乏症一种罕见的表现形式。一名38岁男性,职业为教师,是严格素食者,在进行精细动作时双手突然出现笨拙。进行了详细的病史采集、患者检查及相关检查(全血细胞计数、血清维生素B12和颈髓MRI)。实验室分析提示维生素B12缺乏,MRI显示颈髓后柱有病变。该患者被诊断为因维生素B12缺乏导致的以颈髓后柱为主的非压迫性颈髓病。急性双侧无功能手综合征可能是维生素B12缺乏症一种罕见的表现特征。