Jagid Jonathan, Madhavan Karthik, Bregy Amade, Desai Mehul, Ruiz Armando, Quencer Robert, Landy Howard J
Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA.
Department of Radiology, University of Miami Miller School of Medicine, Miami, Florida, USA.
BMJ Case Rep. 2015 Oct 16;2015:bcr2015211470. doi: 10.1136/bcr-2015-211470.
Deep brain stimulation (DBS) is an approved and effective therapy for patients suffering from advanced Parkinson's disease (PD). Several clinical trials have indicated significant motor function improvement in patients undergoing subthalamic nucleus stimulation. This therapy is, rarely, associated with complications, mostly related to infections, seizures or stimulation-induced side effects. We report a case of a 71-year-old man with a 10-year history of PD who underwent bilateral placement of subthalamic nucleus DBS. As a complication, the patient showed subjective postoperative cognitive decline, and subsequent MRI showed peri-lead oedema, which progressed to large cystic cavitation around the leads without indication of infection. The patient received steroid therapy and the cavitations regressed without surgical intervention.
深部脑刺激（DBS）是一种已获批准且有效的治疗晚期帕金森病（PD）患者的方法。多项临床试验表明，接受丘脑底核刺激的患者运动功能有显著改善。这种治疗很少会出现并发症，主要与感染、癫痫发作或刺激引起的副作用有关。我们报告了一例71岁男性患者，其有10年帕金森病病史，接受了双侧丘脑底核DBS植入术。作为一种并发症，该患者术后出现主观认知功能下降，随后的MRI显示电极周围水肿，进而发展为电极周围大的囊腔形成，且无感染迹象。该患者接受了类固醇治疗，囊腔在未进行手术干预的情况下消退。
