Murphy Erin P, Mo Jun, Yoon Janet M
Departments of *Pediatrics †Pathology, University of California San Diego, San Diego, CA.
J Pediatr Hematol Oncol. 2015 Nov;37(8):e494-6. doi: 10.1097/MPH.0000000000000433.
Secondary hemophagocytic lymphohistiocytosis (HLH) is most commonly associated with malignancy, infection, or an underlying autoimmune disorder. Malignancy-associated hemophagocytic syndrome is responsible for most secondary HLH cases, but it has not been well described in children. We present a case of a 4-year-old female with favorable histology of Wilms tumor who developed secondary HLH after unsuccessful resection of the tumor and initiation of chemotherapy.
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