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以色列北部的非霍奇金淋巴瘤:一项对481例患者的研究,重点关注种族相关模式。

Non-Hodgkin's lymphoma in northern Israel: a study of 481 patients with emphasis on ethnic-related patterns.

作者信息

Cohen Y, Kuten A, Ben-Shahar M, Haim N, Epelbaum R, Ben-Arie Y

机构信息

Northern Israel Oncology Center, Haifa.

出版信息

J Surg Oncol. 1989 Apr;40(4):241-4. doi: 10.1002/jso.2930400408.

Abstract

During the period between 1970-1984, 481 patients with previously untreated non-Hodgkin's lymphoma were referred to the Northern Israel Oncology Center, Haifa. There were 264 (54.9%) Ashkenazi Jews, 123 (25.6%) non-Ashkenazi Jews, and 86 (17.9%) Arabs. The mean age at diagnosis was 60 +/- 15 years for Ashkenazi Jews, 45 +/- 22 years for non-Ashkenazi Jews, and 36 +/- 22 years for Arabs. Ashkenazi Jews had a higher rate of nodular lymphoma compared to non-Ashkenazi Jews and Arabs. Extranodal lymphoma occurred more frequently in non-Ashkenazi Jews and Arabs. Lymphoma of the small intestine was more common in Arabs than in Ashkenazi and non-Ashkenazi Jews. Despite these differences in the pattern of disease, 5 year actuarial survival figures for the various ethnic groups were similar.

摘要

在1970年至1984年期间,481例先前未经治疗的非霍奇金淋巴瘤患者被转诊至海法的以色列北部肿瘤中心。其中有264例(54.9%)阿什肯纳兹犹太人,123例(25.6%)非阿什肯纳兹犹太人,以及86例(17.9%)阿拉伯人。阿什肯纳兹犹太人确诊时的平均年龄为60±15岁,非阿什肯纳兹犹太人为45±22岁,阿拉伯人为36±22岁。与非阿什肯纳兹犹太人和阿拉伯人相比,阿什肯纳兹犹太人的结节性淋巴瘤发病率更高。结外淋巴瘤在非阿什肯纳兹犹太人和阿拉伯人中更为常见。小肠淋巴瘤在阿拉伯人中比在阿什肯纳兹犹太人和非阿什肯纳兹犹太人中更为常见。尽管疾病模式存在这些差异,但各民族的5年精算生存率数据相似。

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