[脑机接口、闭锁综合征与意识障碍]

[Brain-computer interfaces, Locked-In syndrome, and disorders of consciousness].

作者信息

Lesenfants Damien, Chatelle Camille, Laureys Steven, Noirhomme Quentin

机构信息

Coma Science Group, Cyclotron research centre and neurology department, université de Liège, allée du 6 Août, Sart Tilman, 4000 Liège, Belgique - School of engineering and institute for brain science, Brown university, 2 Stimson avenue, 02912 Providence, Rhode Island, États-Unis.

Coma Science Group, Cyclotron research centre and neurology department, université de Liège, allée du 6 Août, Sart Tilman, 4000 Liège, Belgique - Laboratory for neuroimaging of coma and consciousness, Massachusetts general hospital, Boston, Massachusetts, États-Unis - Department of physical medicine and rehabilitation, Spaulding rehabilitation hospital and Harvard medical school, Boston, Massachusetts, États-Unis.

出版信息

Med Sci (Paris). 2015 Oct;31(10):904-11. doi: 10.1051/medsci/20153110017. Epub 2015 Oct 19.

DOI:10.1051/medsci/20153110017

PMID:26481030

Abstract

Detecting signs of consciousness in patients with severe brain injury constitutes a real challenge for clinicians. The current gold standard in clinical diagnosis is the behavioral scale relying on motor abilities, which are often impaired or nonexistent in these patients. In this context, brain-computer interfaces (BCIs) could offer a potential complementary tool to detect signs of consciousness whilst bypassing the usual motor pathway. In addition to complementing behavioral assessments and potentially reducing error rate, BCIs could also serve as a communication tool for paralyzed but conscious patients, e.g., suffering from Locked-In Syndrome. In this paper, we report on recent work conducted by the Coma Science Group on BCI technology, aiming to optimize diagnosis and communication in patients with disorders of consciousness and Locked-In syndrome.

摘要

对于临床医生而言，检测重型脑损伤患者的意识迹象是一项实实在在的挑战。目前临床诊断的金标准是依赖运动能力的行为量表，而这些患者的运动能力往往受损或不存在。在此背景下，脑机接口（BCI）可以提供一种潜在的辅助工具，绕过通常的运动通路来检测意识迹象。除了补充行为评估并可能降低错误率外，脑机接口还可以作为瘫痪但有意识患者（例如患有闭锁综合征的患者）的沟通工具。在本文中，我们报告了昏迷科学小组最近在脑机接口技术方面开展的工作，旨在优化意识障碍和闭锁综合征患者的诊断与沟通。