Hamilton D R
Laboratory Service, Alvin C. York Veterans Administration Medical Center, Murfreesboro, TN 37130.
Postgrad Med. 1989 Apr;85(5):303-8, 313-4. doi: 10.1080/00325481.1989.11700674.
Physicians will recognize Lyme disease faster if they maintain a high index of suspicion in a young patient with arthritis accompanied by negative rheumatoid factor and antinuclear antibody in combination with cardiac conduction problems or lymphocytic meningitis. The Lyme spirochete (Borrelia burgdorferi) has notable sensitivity to tetracycline, penicillin, and erythromycin; therefore, proper and complete treatment of the disease, once it is identified, can be easily achieved. Finkel observed that Lyme disease manifests itself as a "great imitator," as do many disorders caused by a spirochete. The total impact of Lyme disease on public health will be known only when the disease is fully recognized, consistently reported, and adequately managed.
如果医生对患有关节炎、类风湿因子和抗核抗体均为阴性,同时伴有心脏传导问题或淋巴细胞性脑膜炎的年轻患者保持高度怀疑指数,就能更快地识别莱姆病。莱姆螺旋体(伯氏疏螺旋体)对四环素、青霉素和红霉素具有显著敏感性;因此,一旦确诊,对该病进行恰当且彻底的治疗很容易实现。芬克尔观察到,莱姆病如同许多由螺旋体引起的疾病一样,表现为一种“强大的模仿者”。只有当莱姆病得到充分认识、持续报告并得到妥善管理时,才能知晓其对公众健康的总体影响。