Goetz Jillian J, Trimarchi Jeffrey M
Department of Genetics, Development and Cell Biology, 2114 Molecular Biology, Iowa State University, Ames, IA 50011, USA.
Genom Data. 2015 Apr 1;4:88-9. doi: 10.1016/j.gdata.2015.03.010. eCollection 2015 Jun.
In this article, we further explore the data generated for the research article "Onecut1 and Onecut2 play critical roles in the development of the mouse retina". To better understand the functionality of the Onecut family of transcription factors in retinogenesis, we investigated the retinal transcriptomes of developing and mature mice to identify genes with differential expression. This data article reports the full transcriptomes resulting from these experiments and provides tables detailing the differentially expressed genes between wildtype and Onecut1 or 2 deficient retinas. The raw array data of our transcriptomes as generated using Affymetrix microarrays are available on the NCBI Gene Expression Omnibus (GEO) browser (Reference number GSE57917 and GSE57918GSE57917GSE57918).
在本文中，我们进一步探究了为研究论文《Onecut1和Onecut2在小鼠视网膜发育中起关键作用》所生成的数据。为了更好地理解Onecut转录因子家族在视网膜生成中的功能，我们研究了发育中和成熟小鼠的视网膜转录组，以鉴定差异表达的基因。本数据文章报告了这些实验产生的完整转录组，并提供了详细列出野生型与Onecut1或2缺陷型视网膜之间差异表达基因的表格。我们使用Affymetrix微阵列生成的转录组原始阵列数据可在NCBI基因表达综合数据库（GEO）浏览器上获取（参考编号GSE57917和GSE57918GSE57917GSE57918）。
