Durst Christopher R, Hixson H Robert, Schmitt Paul, Gingras Jean M, Crowley R Webster
Department of Radiology and Medical Imaging, University of Virginia Health System, Charlottesville, Virginia, USA.
Department of Neurosurgery, University of Virginia Health System, Charlottesville, Virginia, USA.
World Neurosurg. 2016 Feb;86:511.e1-4. doi: 10.1016/j.wneu.2015.10.016. Epub 2015 Oct 17.
Peripheral fusiform cerebral aneurysms remain difficult to treat. Current surgical approaches to the treatment of fusiform aneurysms include wrapping, clip occlusion or vessel reconstruction without parent vessel sacrifice, and aneurysm trapping with or without bypass, although these may carry high morbidity (36%). Classic endovascular approaches to the treatment of peripheral aneurysms include selective or parent artery occlusion, which imparts the risk of distal infarction. It may be possible to use a flow diversion device off label to treat the aneurysm and preserve flow to the distal territory.
After a presyncopal event, a patient was found to have an unruptured fusiform aneurysm at the junction of the M3 and M4 segments of the right middle cerebral artery. After initiating dual antiplatelet therapy, the aneurysm was successfully treated with a Pipeline embolization device. Three months after treatment, the aneurysm has completely thrombosed, the parent artery remains widely patent, and the patient remains at her neurologic baseline.
Flow diversion devices may provide the neurointerventional surgeon with an opportunity to treat fusiform peripheral aneurysms and preserve flow to the distal territory.
周围性梭形脑动脉瘤的治疗仍然困难。目前治疗梭形动脉瘤的手术方法包括包裹、夹闭或不牺牲母血管的血管重建,以及有或无搭桥的动脉瘤夹闭术,尽管这些方法可能具有较高的发病率(36%)。经典的外周动脉瘤血管内治疗方法包括选择性或母动脉闭塞,这会带来远端梗死的风险。使用未获批准的血流导向装置治疗动脉瘤并保留向远端区域的血流可能是可行的。
一名患者在发生晕厥前事件后,被发现右侧大脑中动脉M3和M4段交界处有一个未破裂的梭形动脉瘤。在开始双重抗血小板治疗后,该动脉瘤成功地用Pipeline栓塞装置进行了治疗。治疗三个月后,动脉瘤已完全血栓形成,母动脉仍广泛通畅,患者仍保持神经功能基线状态。
血流导向装置可能为神经介入外科医生提供治疗周围性梭形动脉瘤并保留向远端区域血流的机会。