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使用氰基丙烯酸正丁酯胶水对颅内周围动脉破裂动脉瘤进行栓塞:病例系列

Embolization of Ruptured Aneurysms in the Intracranial Peripheral Arteries Using N-Butyl Cyanoacrylate Glue: A Case Series.

作者信息

Sakai Yosuke, Tsukada Tetsuya, Watanabe Toru, Araki Yoshio, Seki Yukio

机构信息

Neurosurgery, Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital, Nagoya, JPN.

出版信息

Cureus. 2024 Oct 7;16(10):e71028. doi: 10.7759/cureus.71028. eCollection 2024 Oct.

Abstract

Ruptured aneurysms in peripheral arteries are rare, and an optimal treatment strategy has not yet been established. Herein, we evaluated the efficacy and safety of endovascular treatment of peripheral aneurysms located in small, tortuous vessels. In the present study, we report five consecutive cases of small, peripherally located ruptured aneurysms successfully embolized using N-butyl cyanoacrylate glue, with or without the adjunct use of coils. Five ruptured fusiform peripheral artery aneurysms in five consecutive patients were treated with parent artery occlusion using N-butyl cyanoacrylate glue. The etiologies included a flow-related feeder aneurysm associated with cerebral arteriovenous malformation in one case, a mycotic aneurysm associated with infective endocarditis in one case, and unknown causes in three cases. The procedural safety was assessed in advance using a provocation test in combination with the test occlusion of the parent artery with a coil, as required. Complete occlusion of the aneurysm was achieved in all patients, and no instances of postoperative symptomatic cerebral infarction were observed. The patients who attended follow-up showed no recurrence of aneurysms. This study shows that small peripheral artery aneurysms can be effectively embolized endovascularly with high therapeutic efficacy, using an appropriately sized microcatheter, after conducting a thorough safety assessment of parent artery occlusion.

摘要

外周动脉破裂性动脉瘤较为罕见,目前尚未确立最佳治疗策略。在此,我们评估了血管内治疗位于细小、迂曲血管中的外周动脉瘤的疗效和安全性。在本研究中,我们报告了连续5例位于外周的破裂性小动脉瘤,使用氰基丙烯酸正丁酯胶水(无论是否辅助使用弹簧圈)成功进行了栓塞。连续5例患者的5个破裂性梭形外周动脉动脉瘤采用氰基丙烯酸正丁酯胶水闭塞载瘤动脉进行治疗。病因包括1例与脑动静脉畸形相关的血流相关供血动脉瘤、1例与感染性心内膜炎相关的霉菌性动脉瘤以及3例病因不明。根据需要,预先通过激发试验并结合用弹簧圈对载瘤动脉进行试验性闭塞来评估手术安全性。所有患者的动脉瘤均实现完全闭塞,未观察到术后有症状性脑梗死的病例。接受随访的患者未出现动脉瘤复发。本研究表明,在对载瘤动脉闭塞进行全面安全性评估后,使用尺寸合适的微导管,外周小动脉动脉瘤可通过血管内有效栓塞,具有较高的治疗效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d26/11540465/4528789c9dae/cureus-0016-00000071028-i01.jpg

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