Knuttel Floortje M, van den Bosch Maurice A A J
Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands.
Adv Exp Med Biol. 2016;880:65-81. doi: 10.1007/978-3-319-22536-4_4.
This chapter describes several aspects of MR-HIFU treatment for breast cancer. The current and future applications, technical developments and clinical results are discussed. MR-HIFU ablation is under investigation for the treatment of breast cancer, but is not yet ready for clinical implementation. Firstly, the efficacy of MR-HIFU ablation should be investigated in large trials. The existing literature shows that results of initial, small studies are moderate, but opportunities for improvement are available. Careful patient selection, taking treatment margins into account and using a dedicated breast system might improve treatment outcomes. MRI-guidance has proven to be beneficial for the accuracy and safety of HIFU treatments because of its usefulness before, during and after treatments. In conclusion, MR-HIFU is promising for the treatment of breast cancer and might lead to a change in breast cancer care in the future.
本章描述了磁共振引导高强度聚焦超声（MR-HIFU）治疗乳腺癌的几个方面。讨论了其当前和未来的应用、技术发展以及临床结果。MR-HIFU消融术正在进行乳腺癌治疗的研究，但尚未准备好临床应用。首先，应在大型试验中研究MR-HIFU消融术的疗效。现有文献表明，最初的小型研究结果一般，但仍有改进的空间。仔细选择患者、考虑治疗边界并使用专用乳腺系统可能会改善治疗效果。由于MRI引导在治疗前、治疗期间和治疗后的实用性，已证明其对HIFU治疗的准确性和安全性有益。总之，MR-HIFU在乳腺癌治疗方面前景广阔，未来可能会改变乳腺癌的治疗方式。
