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加兰·艾伦、托马斯·亨特·摩根与发育

Garland Allen, Thomas Hunt Morgan, and Development.

作者信息

Maienschein Jane

机构信息

Center for Biology and Society, School of Life Sciences, Arizona State University, Tempe, AZ, 85287-4501, USA.

Marine Biological Laboratory, Woods Hole, MA, 02543, USA.

出版信息

J Hist Biol. 2016 Dec;49(4):587-601. doi: 10.1007/s10739-015-9426-3.

Abstract

Garland E. Allen's 1978 biography of the Nobel Prize winning biologist Thomas Hunt Morgan provides an excellent study of the man and his science. Allen presents Morgan as an opportunistic scientist who follows where his observations take him, leading him to his foundational work in Drosophila genetics. The book was rightfully hailed as an important achievement and it introduced generations of readers to Morgan. Yet, in hindsight, Allen's book largely misses an equally important part of Morgan's work - his study of development and regeneration. It is worth returning to this part of Morgan, exploring what Morgan contributed and also why he has been seen by contemporaries and historians such as Allen as having set aside some of the most important developmental problems. A closer look shows how Morgan's view of cells and development that was different from that of his most noted contemporaries led to interpretation of his important contributions in favor of genetics. This essay is part of a special issue, revisiting Garland Allen's views on the history of life sciences in the twentieth century.

摘要

加兰·E·艾伦1978年所著的关于诺贝尔奖得主生物学家托马斯·亨特·摩根的传记,对这位科学家及其科学成就进行了出色的研究。艾伦将摩根描绘成一位机会主义科学家,他追随自己的观察结果,从而引领他在果蝇遗传学领域开展了奠基性工作。这本书理所当然地被誉为一项重要成就,它让几代读者认识了摩根。然而,事后看来,艾伦的这本书在很大程度上忽略了摩根工作中同样重要的一部分——他对发育和再生的研究。值得重新审视摩根的这部分工作,探究摩根做出了哪些贡献,以及为何他被艾伦等同时代人和历史学家视为搁置了一些最重要的发育问题。仔细审视会发现,摩根对细胞和发育的观点与他最著名的同时代人不同,这导致了对他重要贡献的解读偏向遗传学。本文是一个特刊的一部分,旨在重新审视加兰·艾伦对20世纪生命科学史的观点。

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