Retz-Junginger Petra, Rösler Michael, Giesen Lisa Katharina, Philipp-Wiegmann Florence, Römer Konstanze, Zinnow Toivo, Retz Wolfgang
Institut für gerichtliche Psychologie und Psychiatrie, Universitätsklinikum des Saarlandes, Homburg/Saar.
Forensische Psychiatrie und Psychotherapie, Universitätsmedizin Mainz.
Psychiatr Prax. 2016 Jul;43(5):279-82. doi: 10.1055/s-0035-1552699. Epub 2015 Oct 21.
In consideration of ADHD subtype we assessed burden of disease of adult ADHD patients and neuroticism.
511 adult ADHD patients were enrolled in the study. We measured ADHD symptoms categorically and dimensionally by the "Homburger ADHS-Skalen für Erwachsene (HASE)". All participants rated their ADHD associated level of suffering. To assess personality traits, the psychometric instrument NEO-PI-R was used.
In patients with higher levels of neuroticism, there was no significant difference in the level of suffering between the ADHD subtypes. In the group of ADHD patients which scored low on the neuroticism scale, ADHD combined patients are significant more affected compared to the predominantly hyperactive-impulsive or the predominantly inattentive type.
These results underline the hypothesis that the burden of disease is not only related to the level of ADHD symptoms and subtype but also moderated by neuroticism.
考虑到注意缺陷多动障碍（ADHD）的亚型，我们评估了成年ADHD患者的疾病负担和神经质水平。
511名成年ADHD患者参与了该研究。我们通过“汉堡成人ADHD量表（HASE）”对ADHD症状进行分类和维度测量。所有参与者对其与ADHD相关的痛苦程度进行评分。为评估人格特质，使用了心理测量工具NEO-PI-R。
在神经质水平较高的患者中，ADHD各亚型之间的痛苦程度无显著差异。在神经质量表得分较低的ADHD患者组中，与以多动冲动为主型或注意力不集中为主型相比，ADHD混合型患者受影响更显著。
这些结果支持了以下假设，即疾病负担不仅与ADHD症状水平和亚型有关，还受神经质的调节。
