Wong Jonathan M, Fisher Mark
a Department of Medicine , California Pacific Medical Center , San Francisco , CA , USA.
b Department of Neurology , University of California , Irvine , CA , USA.
Expert Rev Cardiovasc Ther. 2016;14(1):1-3. doi: 10.1586/14779072.2015.1100536. Epub 2015 Oct 21.
The left atrial septal pouch (LASP) is an anatomic variant of the atrial septum that forms a blind-ending pouch, communicating exclusively with the left atrium (LA). Case reports have demonstrated thrombus within LASP and in the setting of cryptogenic stroke. Initial epidemiologic results are mixed, one study showing and others not showing an association between LASP and cryptogenic stroke. Additional investigation should take place to determine the clinical significance of LASP and what interventions are required to prevent ischemic stroke in at-risk individuals.
左心房间隔袋(LASP)是房间隔的一种解剖变异,形成一个盲端袋,仅与左心房(LA)相通。病例报告显示LASP内有血栓形成,并与不明原因的卒中有关。初步的流行病学结果不一,一项研究显示LASP与不明原因的卒中有关,而其他研究则未显示这种关联。应进行进一步调查,以确定LASP的临床意义以及对有风险的个体预防缺血性卒中需要采取哪些干预措施。