Xiong Glen L, Filshtein Teresa, Beckett Laurel A, Hinton Ladson
From the Dept. of Psychiatry and Behavioral Sciences (GLX, LH) and the Division of Biostatistics, Dept. of Public Health Sciences (TF, LAB), Alzheimer's Disease Center, and the Latino Aging Resource Center (LH), University of California, Davis.
J Neuropsychiatry Clin Neurosci. 2015 Fall;27(4):326-32. doi: 10.1176/appi.neuropsych.15010020.
A cross-sectional analysis examined medication records in the National Alzheimer's Coordinating Center Database for community-dwelling patients with dementia who visited an Alzheimer's Disease Center between 2008 and 2014. Hispanic participants had a 1.62-fold greater use of antipsychotic medications, which was largely accounted for by a higher prevalence of neuropsychiatric symptoms and more severe dementia compared with non-Hispanic whites. These results are consistent with reports of later transition to nursing home care among Hispanic participants. Further studies are needed to clarify ethnic differences in how families and physicians address dementia progression and neuropsychiatric symptoms in community-dwelling patients with dementia.
一项横断面分析研究了国家阿尔茨海默病协调中心数据库中2008年至2014年间前往阿尔茨海默病中心就诊的社区痴呆患者的用药记录。西班牙裔参与者使用抗精神病药物的频率高出1.62倍，这主要是由于与非西班牙裔白人相比，神经精神症状的患病率更高且痴呆更为严重。这些结果与西班牙裔参与者向养老院护理过渡较晚的报道一致。需要进一步研究以阐明在社区痴呆患者中，家庭和医生在应对痴呆进展和神经精神症状方面的种族差异。
