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关于专利过期药物在精神疾病中使用情况的调查:精神科医生和神经科医生的意见与能力

[A survey on the use of patent expired drugs in psychiatric disorders: the psychiatrists' and neurologists' opinion and competence].

作者信息

Bersani Giuseppe

机构信息

Dipartimento di Scienze e Biotecnologie Medico-Chirurgiche, Sapienza Università di Roma.

出版信息

Riv Psichiatr. 2015 Sep-Oct;50(5):228-38. doi: 10.1708/2040.22164.

Abstract

The use of generic drugs is an increasing phenomenon in Italy, as well as in most other Countries. In front of this, the level of information of medical doctors about their characteristics is still frequently uncompletely defined and insufficiently documented. The Survey "InfoMind" explored by an on line questionnaire the level of knowledge and the principal modes of use of generic drugs in a wide group of Italian Psychiatrists and Neurologists. The attention was focused on the use of generic drugs both in general and in the field of antidepressant treatments. In the group of participants (246) who fulfilled the questionnaire, a valid degree of attention to the critical issues related to the use of generic drugs and a variable level of information with respect to the explored areas were found. Main topics of discordant opinions were those of the pharmacokinetic differences among generic and original drugs, the related potential influence on clinical response, the regulatory rules on production and quality control of generic drugs respect to original. The main issues emerged as critical also respect the use of antidepressant drugs. Also the opinions regarding the legal implications of the choice of prescribed drugs appear variable and of the greatest interest.

摘要

在意大利以及大多数其他国家,使用非专利药的现象日益普遍。面对这种情况,医生们对非专利药特性的了解程度往往仍未完全明确且记录不足。“InfoMind调查”通过在线问卷探究了广大意大利精神科医生和神经科医生对非专利药的了解程度及主要使用方式。调查重点关注了非专利药在一般情况下以及抗抑郁治疗领域的使用。在完成问卷的参与者群体(246人)中,发现他们对与使用非专利药相关的关键问题有一定程度的关注,但在调查领域的信息水平参差不齐。意见不一致的主要话题包括非专利药与原研药之间的药代动力学差异、其对临床反应的潜在影响、非专利药相对于原研药在生产和质量控制方面的监管规定。在抗抑郁药物的使用方面也出现了一些关键问题。关于处方药选择的法律影响的意见也各不相同,且最受关注。

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