Kaneshiro Kazumi, Takatsuki Kiyonobu, Kanamori Kiyonobu
Kekkaku. 2015 Apr;90(4):457-61.
A 54-year-old man was admitted to our hospital because of fever, dyspnea, and low back pain. Chest computed tomography showed a 30-mm mass in the left lung and bilateral pleural fluids, multiple bone lesions, enlarged lymph nodes, and skin abscesses. Mycobacterium avium was isolated from his sputum, a pleural fluid sample, the right cervical lymph node, and a precordial skin abscess. We thus diagnosed his illness as disseminated nontuberculous mycobacterial infection (DNTM) and treated him with multiple chemotherapeutic agents. However, the disease progressed, and he ultimately died. He was not in an obvious immunocompromised state. DNTM with multiple bone lesions in a healthy adult is very rare and we therefore report this case.
一名54岁男性因发热、呼吸困难和腰痛入院。胸部计算机断层扫描显示左肺有一个30毫米的肿块以及双侧胸腔积液、多处骨病变、淋巴结肿大和皮肤脓肿。从他的痰液、一份胸腔积液样本、右颈部淋巴结和心前区皮肤脓肿中分离出鸟分枝杆菌。因此，我们将他的病情诊断为播散性非结核分枝杆菌感染（DNTM），并用多种化疗药物对他进行治疗。然而，病情仍在进展，他最终死亡。他并非处于明显的免疫功能低下状态。健康成年人发生伴有多处骨病变的DNTM非常罕见，因此我们报告了此病例。
