通过唾液酸印迹纳米标签对癌细胞和组织进行表面增强拉曼散射成像。
Surface-enhanced Raman scattering imaging of cancer cells and tissues via sialic acid-imprinted nanotags.
作者信息
Yin Danyang, Wang Shuangshou, He Yunjie, Liu Jia, Zhou Min, Ouyang Jian, Liu Baorui, Chen Hong-Yuan, Liu Zhen
机构信息
State Key Laboratory of Analytical Chemistry for Life Science and Collaborative Innovation Center of Chemistry for Life Sciences, School of Chemistry and Chemical Engineering, Nanjing University, 22 Hankou Road, Nanjing 210093, China.
The Comprehensive Cancer Center of Drum Tower Hospital, Clinical College of Nanjing Medical University, Zhongshan Road 321, Nanjing 21008, China.
出版信息
Chem Commun (Camb). 2015 Dec 28;51(100):17696-9. doi: 10.1039/c5cc05174f.
Molecularly imprinted nanoparticles were prepared as surface-enhanced Raman scattering tags for the selective imaging of cancer cells and tissues against normal cells and tissues relying on the use of sialic acid-templated imprinting to recognize cancer cells, which are over-expressed with sialic acid at the surface.
分子印迹纳米颗粒被制备为表面增强拉曼散射标签，用于针对正常细胞和组织选择性成像癌细胞和组织，这依赖于使用唾液酸模板印迹来识别在表面过度表达唾液酸的癌细胞。
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