Garnier Maylis, Sabbah Michèle, Ménager Christine, Griffete Nébéwia
PHysico-Chimie des Electrolytes et Nanosystèmes InterfaciauX (PHENIX), Sorbonne Université, CNRS, 4 Place Jussieu, F-75005 Paris, France.
Saint-Antoine Research Center (CRSA), INSERM, CNRS, Sorbonne Université, F-75012 Paris, France.
Nanomaterials (Basel). 2021 Nov 16;11(11):3091. doi: 10.3390/nano11113091.
Molecularly imprinted polymers (MIPs) have been widely used in nanomedicine in the last few years. However, their potential is limited by their intrinsic properties resulting, for instance, in lack of control in drug release processes or complex detection for in vivo imaging. Recent attempts in creating hybrid nanomaterials combining MIPs with inorganic nanomaterials succeeded in providing a wide range of new interesting properties suitable for nanomedicine. Through this review, we aim to illustrate how hybrid molecularly imprinted polymers may improve patient care with enhanced imaging, treatments, and a combination of both.
近年来，分子印迹聚合物（MIPs）已在纳米医学中得到广泛应用。然而，其潜力受到其固有特性的限制，例如在药物释放过程中缺乏控制或体内成像的复杂检测。最近将MIPs与无机纳米材料相结合制备杂化纳米材料的尝试成功地提供了一系列适用于纳米医学的新的有趣特性。通过本综述，我们旨在说明杂化分子印迹聚合物如何通过增强成像、治疗以及两者的结合来改善患者护理。
