卡托普利试验：对高血压调查的一种辅助手段。
The captopril test: an aid to investigation of hypertension.
作者信息
Daman Willems C E, Shah V, Uchiyama M, Dillon M J
机构信息
Renal Unit, Hospital for Sick Children, London.
出版信息
Arch Dis Child. 1989 Feb;64(2):229-34. doi: 10.1136/adc.64.2.229.
Abstract
Twenty three children aged from 5 to 16 with mild to moderate hypertension were investigated using the orally active angiotensin converting enzyme inhibitor captopril. Falls in both systolic and diastolic blood pressure after a single dose of captopril were significantly correlated with initial plasma renin activity. In addition, some information about the aetiology of hypertension was deduced from the renin response to captopril. The blood pressure response to captopril is a useful screening test for renin dependent hypertension in childhood.
摘要
对23名年龄在5至16岁之间患有轻度至中度高血压的儿童使用口服活性血管紧张素转换酶抑制剂卡托普利进行了研究。单次服用卡托普利后收缩压和舒张压的下降与初始血浆肾素活性显著相关。此外，从对卡托普利的肾素反应中推断出了一些关于高血压病因的信息。卡托普利的血压反应是儿童肾素依赖性高血压的一种有用筛查试验。
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The captopril test: an aid to investigation of hypertension.卡托普利试验：对高血压调查的一种辅助手段。
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本文引用的文献
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Lancet. 1963 Jun 22;1(7295):1354-6. doi: 10.1016/s0140-6736(63)91929-9.
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Factors related to first dose hypotensive effect of captopril: prediction and treatment.卡托普利首剂降压效应的相关因素：预测与治疗
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The captopril test for identifying renovascular disease in hypertensive patients.卡托普利试验用于识别高血压患者的肾血管疾病。
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Plasma renin activity and aldosterone concentration in children.儿童的血浆肾素活性和醛固酮浓度
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J Clin Pathol. 1975 Aug;28(8):625-30. doi: 10.1136/jcp.28.8.625.
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Blood pressure and hypertension in childhood and adolescence.儿童及青少年时期的血压与高血压
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Use of an angiotensin II antagonist (saralasin) in the recognition of "angiotensinogenic" hypertension;
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Reactive hyper-reninaemia to angiotensin blockade identifies renovascular hypertension.
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