卡托普利试验在肾血管性和肾性高血压患儿中的应用
The captopril test in children with renovascular and renal hypertension.
作者信息
Fossali E, Intermite R, Minoja M, Tirelli S, Sereni F
机构信息
Clinica pediatrica II, Università di Milano, Italy.
出版信息
Acta Paediatr. 1996 Sep;85(9):1129-31. doi: 10.1111/j.1651-2227.1996.tb14232.x.
We used the captopril test (CT) in 32 children, 8 with renovascular hypertension (RVH), 17 with renal hypertension (RH) and 7 with normal blood pressure, in order to study the renin-angiotensin system activation (RASA). All children affected by RVH presented a positive CT: a post-captopril plasma renin activity (PRA) of 12 ng ml-1 h-1 or more, an absolute PRA increase of 10 ng ml-1 h-1 or more and a 150% increase or more, or 400% or more if the baseline PRA was less than 3 ng ml-1 h-1. The CT may be useful for demonstrating the RASA in RVH.
我们对32名儿童进行了卡托普利试验（CT），其中8名患有肾血管性高血压（RVH），17名患有肾性高血压（RH），7名血压正常，以研究肾素-血管紧张素系统激活（RASA）情况。所有受RVH影响的儿童CT结果均为阳性：卡托普利给药后血浆肾素活性（PRA）为12 ng ml-1 h-1或更高，PRA绝对增加值为10 ng ml-1 h-1或更高，且增加150%或更多；如果基线PRA低于3 ng ml-1 h-1，则增加400%或更多。CT可能有助于证明RVH中的RASA情况。
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