Castro-Navarro Veronica, Odaibo Stephen G, Ghodasra Devon H, Besirli Cagri G
Hospital General Universitario de Valencia, Valencia, Spain Kellogg Eye Center, University of Michigan, Ann Arbor, Michigan, USA.
Kellogg Eye Center, University of Michigan, Ann Arbor, Michigan, USA.
BMJ Case Rep. 2015 Oct 21;2015:bcr2015212463. doi: 10.1136/bcr-2015-212463.
Bilateral cases of branch retinal vein occlusions (BRVO) are infrequent and often related to systemic disease. A 72-year-old man with biochemical recurrence of prostate cancer was referred for decreased vision in his left eye. Fundus examination and fluorescein angiography disclosed bilateral BRVO with patches of peripheral non-perfusion and macular oedema in the left eye. A systemic work up revealed elevated fibrinogen and reduced free protein S antigen, consistent with an underlying hypercoagulable state. Cancer is a well-known cause of hypercoagulability. We report the first case of bilateral BRVO related to biochemical recurrence of prostate cancer and a proven coagulation derangement.
双侧视网膜分支静脉阻塞（BRVO）病例并不常见，且常与全身性疾病相关。一名72岁前列腺癌生化复发的男性因左眼视力下降前来就诊。眼底检查和荧光素血管造影显示双侧BRVO，左眼有周边部无灌注区和黄斑水肿。全身检查发现纤维蛋白原升高和游离蛋白S抗原降低，符合潜在的高凝状态。癌症是高凝状态的一个众所周知的原因。我们报告了首例与前列腺癌生化复发及已证实的凝血紊乱相关的双侧BRVO病例。
