Madanagopalan V G, Paneer Selvam V, Sarath Sivan N V, Govindaraju N V
Arasan Eye Hospital, Erode, India.
GMS Ophthalmol Cases. 2019 Feb 12;9:Doc04. doi: 10.3205/oc000093. eCollection 2019.
Systemic malignancies may have ocular manifestations in the form of metastatic tumors, carcinoma associated retinopathy or central retinal vein occlusion (CRVO). Although CRVO has been mentioned in association with renal, lung, prostatic and ovarian malignancies, the association of CRVO with breast carcinoma is unreported. We report a patient with one such rare association. We describe a patient with breast carcinoma who was diagnosed to have CRVO. The history, ocular examination, retinal optical coherence tomography scan, ocular ultrasound scan, hematological profile, mammogram details and aspiration cytology description of the malignant breast lesion are reported in this article. The retina showed extensive hemorrhages and dilated retinal veins. Complete hematologic evaluation revealed the presence of microcytic hypochromic anemia and increased hematocrit. These changes are possibly related to the malignant disease and might contribute to the pathogenesis of CRVO. This case report demonstrates the rare association between breast malignancy and CRVO.
全身性恶性肿瘤可能会以转移性肿瘤、癌相关性视网膜病变或视网膜中央静脉阻塞（CRVO）的形式出现眼部表现。尽管CRVO已被提及与肾、肺、前列腺和卵巢恶性肿瘤有关，但CRVO与乳腺癌的关联尚未见报道。我们报告了一位有这种罕见关联的患者。我们描述了一位被诊断患有CRVO的乳腺癌患者。本文报告了该患者的病史、眼部检查、视网膜光学相干断层扫描、眼部超声扫描、血液学检查结果、乳房X线照片细节以及恶性乳腺病变的穿刺细胞学描述。视网膜显示广泛出血和视网膜静脉扩张。全面的血液学评估显示存在小细胞低色素性贫血和血细胞比容升高。这些变化可能与恶性疾病有关，并可能促成CRVO的发病机制。本病例报告证明了乳腺恶性肿瘤与CRVO之间的罕见关联。
