Kim Youngjoon, Kim Hyunjung
Department of Plastic and Reconstructive Surgery, Sanggye Paik Hospital, Inje University College of Medicine, 1342 Dongil-ro, Nowon-gu, Seoul 139-707, Republic of Korea.
Department of Pathology, Sanggye Paik Hospital, Inje University College of Medicine, 1342 Dongil-ro, Nowon-gu, Seoul 139-707, Republic of Korea.
Case Rep Med. 2015;2015:589831. doi: 10.1155/2015/589831. Epub 2015 Sep 30.
Cutaneous ciliated cyst was described as a painless cyst occurring on the lower limbs of women between the ages of 15 and 30 years. The cysts are typically lined by ciliated cuboidal to columnar epithelium with pseudostratified areas and focal squamous metaplasia is occasionally present. Immunohistochemical studies have demonstrated that the cysts are PR and ER positive, similar to the epithelia of the fallopian tubes. However, outliers of cutaneous ciliated cysts, including those in male patients and in unexpected locations such as the scalp, finger, and scapular area, have been reported. Thus, some hypotheses have been proposed including the Mullerian heterotopias, ciliated metaplasia of eccrine sweat glands, and embryonic remnants of the cloacal membrane. We report a rare case of cutaneous ciliated cyst on the left shoulder of a 7-year-old boy and this is the eighth case of cutaneous ciliated cyst in male patients. Moreover, through reviewing the articles, we try to propose the classification of the cutaneous ciliated cysts into the cutaneous Mullerian cysts and the ciliated cutaneous eccrine cysts.
皮肤纤毛囊肿被描述为一种发生在15至30岁女性下肢的无痛性囊肿。囊肿通常内衬纤毛立方上皮至柱状上皮,有假复层区域,偶尔可见局灶性鳞状化生。免疫组织化学研究表明,这些囊肿PR和ER呈阳性,类似于输卵管上皮。然而,已有报道称皮肤纤毛囊肿存在异常情况,包括男性患者以及发生在头皮、手指和肩胛区等意外部位的囊肿。因此,有人提出了一些假说,包括苗勒氏异位、小汗腺纤毛化生以及泄殖腔膜的胚胎残余。我们报告了一例罕见的7岁男孩左肩皮肤纤毛囊肿病例,这是男性患者中第八例皮肤纤毛囊肿。此外,通过回顾文献,我们试图将皮肤纤毛囊肿分为皮肤苗勒氏囊肿和纤毛皮肤小汗腺囊肿。