重型颅脑损伤患者血清失能性亲善目标蛋白质组的测定
Determination of Serum Lost Goodwill Target Proteome in Patients with Severe Traumatic Brain Injury.
作者信息
Ji Hongming, Hu Changchen, Zhang Gangli, Ren Jinrui, Tan Yihu, Sun Wenxiao, Wang Junwen, Li Jun, Liu Hongchao, Xie Ruifan, Hao Zhipeng, Guo Dongsheng
机构信息
Department of Neurosurgery, Shanxi Provincial People's Hospital, Taiyuan 030001, China.
Department of Neurosurgery, Shanxi Provincial People's Hospital, Taiyuan 030001, China ; Department of Neurosurgery, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
出版信息
Biomed Res Int. 2015;2015:183821. doi: 10.1155/2015/183821. Epub 2015 Sep 27.
Abstract
This study investigates the biokinetics of LGT proteome, a potential biomarker of severe TBI, in serum of severe TBI patients. The LGT proteome presents in the serum of severe TBI patients. The abundance diversity of LGT proteome is closely associated with pathologic condition of TBI patients. Serum LGT proteome may be used as a promising marker for evaluating severity of severe TBI.
摘要
本研究调查了严重创伤性脑损伤（TBI）患者血清中LGT蛋白质组的生物动力学，LGT蛋白质组是严重TBI的一种潜在生物标志物。LGT蛋白质组存在于严重TBI患者的血清中。LGT蛋白质组的丰度多样性与TBI患者的病理状况密切相关。血清LGT蛋白质组可能作为评估严重TBI严重程度的一个有前景的标志物。
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