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农业生物技术中的转基因蛋白:毒理学论坛第40届年度夏季会议

Transgenic proteins in agricultural biotechnology: The toxicology forum 40th annual summer meeting.

作者信息

Sherman James H, Choudhuri Supratim, Vicini John L

机构信息

Monsanto Company, Toxicology and Nutrition Center, 800 N. Lindbergh Blvd, St. Louis, MO 63167, USA.

US FDA-CFSAN, Office of Food Additive Safety, 5100 Paint Branch Parkway, College Park, MD 20740, USA.

出版信息

Regul Toxicol Pharmacol. 2015 Dec;73(3):811-8. doi: 10.1016/j.yrtph.2015.10.014. Epub 2015 Oct 19.

Abstract

During the 40th Annual Meeting of The Toxicology Forum, the current and potential future science, regulations, and politics of agricultural biotechnology were presented and discussed. The range of current commercial crops and commercial crop traits related to transgenic proteins were reviewed and example crop traits discussed, including insecticidal resistance conferred by Bt proteins and the development of nutritionally enhanced food such as Golden Rice. The existing regulatory framework in the USA, with an emphasis on US FDA's role in evaluating the safety of genetically engineered crops under the regulatory umbrella of the FD&C Act was reviewed. Consideration was given to the polarized politics surrounding agricultural biotechnology, the rise of open access journals, and the influence of the internet and social media in shaping public opinion. Numerous questions related to misconceptions regarding current products and regulations were discussed, highlighting the need for more scientists to take an active role in public discourse to facilitate public acceptance and adoption of new technologies and to enable science-based regulations.

摘要

在毒理学论坛第40届年会上,介绍并讨论了农业生物技术的当前及潜在未来科学、法规和政治情况。回顾了与转基因蛋白相关的当前商业作物和商业作物性状范围,并讨论了作物性状实例,包括Bt蛋白赋予的抗虫性以及如黄金大米等营养强化食品的开发。审查了美国现有的监管框架,重点是美国食品药品监督管理局(FDA)在《联邦食品、药品和化妆品法案》监管框架下评估转基因作物安全性方面的作用。考虑了围绕农业生物技术的两极分化政治、开放获取期刊的兴起以及互联网和社交媒体在塑造公众舆论方面的影响。讨论了许多与对当前产品和法规的误解相关的问题,强调需要更多科学家积极参与公众讨论,以促进公众接受和采用新技术,并实现基于科学的法规。

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