耐甲氧西林金黄色葡萄球菌：用非耐药性表皮葡萄球菌培养物进行治疗。
Methicillin-Resistant Staphylococcus aureus: Treatment with Cultures of Non Drug-Resistant Staphylococcus epidermidis.
作者信息
Werner Felix-Martin, Covenas Rafael
机构信息
Research Field: Neural Networks in Neurological and Psychiatric Diseases, Euro Akademie Pößneck, Higher Vocational School of Elderly Care and Occupational Therapy, Carl- Gustav-Vogel-Str. 13, 07381 Pößneck, Germany.
出版信息
Recent Pat Antiinfect Drug Discov. 2015;10(2):124-7. doi: 10.2174/1574891x10666150827103448.
The colonization and infection with methicillin-resistant Staphylococcus aureus is a major health problem in hospitals and long-term care facilities. Although bacteriaemias with MRSA (methicillin-resistant Staphylococcus aureus) can be treated with vancomycin and other reserve antibiotics, 20% of patients cannot be successfully cured. Inpatients colonized with MRSA are isolated in hospitals according to the guidelines of the Robert-Koch-Institute, although in long-term care facilities these patients are not urgently isolated. Active decolonization measures are taken to eradicate colonization with MRSA. In order to reduce MRSA colonization, it could be possible to administer cultures of Staphylococcus epidermidis which have no antibiotic resistance, so that physiological genes could be conferred from Staphylococcus epidermidis to MRSA bacteria.
耐甲氧西林金黄色葡萄球菌的定植和感染是医院及长期护理机构中的一个主要健康问题。尽管耐甲氧西林金黄色葡萄球菌（MRSA）引起的菌血症可用万古霉素和其他备用抗生素治疗，但仍有20%的患者无法成功治愈。根据罗伯特·科赫研究所的指南，医院会将定植有MRSA的住院患者隔离，不过在长期护理机构中，这些患者不会被紧急隔离。会采取积极的去定植措施以根除MRSA的定植。为了减少MRSA定植，有可能给予无抗生素耐药性的表皮葡萄球菌培养物，以便将表皮葡萄球菌的生理基因赋予MRSA细菌。
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