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急性胰腺炎作为十二指肠黏膜相关淋巴组织淋巴瘤的首发表现。

Acute pancreatitis as the first manifestation of duodenal MALT lymphoma.

作者信息

Simkova Ivona, Urbanek Karel, Prochazka Vlastimil, Konecny Michal, Gregar Jan, Geierova Marie, Prochazka Vit, Buriankova Eva

机构信息

Department of Internal Medicine II - Gastroenterology and Hepatology, Faculty of Medicine and Dentistry, Palacky University Olomouc and University Hospital Olomouc, Czech Republic.

Department of Pharmacology, Faculty of Medicine and Dentistry, Palacky University Olomouc and University Hospital Olomouc.

出版信息

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2015 Dec;159(4):688-94. doi: 10.5507/bp.2015.047. Epub 2015 Oct 22.

Abstract

BACKGROUND

Possibly any tumor that can cause mechanical obstruction of the distal bile duct can induce acute pancreatitis. However, acute pancreatitis as the first clinical manifestation of duodenal lymphoma is extremely rare.

OBJECTIVE

To report the case of a patient with acute pancreatitis as an extremely rare first manifestation of duodenal MALT lymphoma and possible association with erythema nodosum.

METHODS

Case report of a 66-year-old woman who was diagnosed with acute pancreatitis caused by infiltration with duodenal lymphoma.

RESULTS

Acute pancreatitis was confirmed by CT imaging. Detailed investigation revealed a duodenal mass causing pancreatic injury. Histological analysis established the diagnosis of MALT lymphoma. The patient's medical history also included erythema nodosum. Complete remission of the malignancy was achieved with chemotherapy.

CONCLUSION

This is the first published case report of acute pancreatitis caused by the growth of duodenal MALT lymphoma. An association with erythema nodosum is possible.

摘要

背景

可能任何能够导致远端胆管机械性梗阻的肿瘤都可诱发急性胰腺炎。然而,急性胰腺炎作为十二指肠淋巴瘤的首发临床表现极为罕见。

目的

报告一例急性胰腺炎作为十二指肠黏膜相关淋巴组织(MALT)淋巴瘤极为罕见的首发表现且可能与结节性红斑相关的病例。

方法

对一名66岁女性患者进行病例报告,该患者被诊断为由十二指肠淋巴瘤浸润引起的急性胰腺炎。

结果

CT成像证实为急性胰腺炎。详细检查发现十二指肠肿物导致胰腺损伤。组织学分析确诊为MALT淋巴瘤。患者病史中还包括结节性红斑。化疗使恶性肿瘤完全缓解。

结论

这是首篇发表的关于十二指肠MALT淋巴瘤生长导致急性胰腺炎的病例报告。可能与结节性红斑有关。

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