Lee Kyeong-Tae, Mun Goo-Hyun
Department of Plastic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-dong, Gangnam-gu, Seoul, 135-710, South Korea.
Department of Plastic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-dong, Gangnam-gu, Seoul, 135-710, South Korea.
Am J Surg. 2016 Aug;212(2):336-44. doi: 10.1016/j.amjsurg.2015.07.015. Epub 2015 Sep 30.
The aim of this review is to comprehensively compare the outcomes of one-stage and two-stage prosthesis-based breast reconstruction via meta-analytic methodology.
Seventeen studies comparing one-stage and two-stage prosthesis-based breast reconstruction were reviewed. The analysis divided the outcomes into 3 categories: complications, esthetic satisfaction, and total cost for completing reconstruction.
The one-stage reconstruction group was at significantly higher risk for reconstruction failure and overall complications than the two-stage group. No significant difference was observed between the 2 groups in the results of nipple-sparing mastectomy. The esthetic result analysis demonstrated that both methods showed comparably positive outcomes. The one-stage group incurred lower cost for completing reconstruction than the two-stage group, despite the higher cost for treatment-related complications. Our results suggest that the risks for adverse outcome in patients undergoing one-stage reconstruction may be comparable with that of two-stage reconstruction when performed in patients receiving a nipple-sparing mastectomy. However, further well-controlled studies are required to draw more solid conclusions.
本综述旨在通过荟萃分析方法全面比较一期和二期假体乳房重建的效果。
回顾了17项比较一期和二期假体乳房重建的研究。分析将结果分为3类：并发症、美学满意度和完成重建的总成本。
一期重建组比二期重建组重建失败和总体并发症的风险显著更高。在保乳手术结果方面，两组之间未观察到显著差异。美学结果分析表明，两种方法均显示出相当积极的效果。尽管一期重建组治疗相关并发症的费用较高，但完成重建的费用低于二期重建组。我们的结果表明，接受保乳手术的患者进行一期重建时不良结局的风险可能与二期重建相当。然而，需要进一步进行严格对照研究以得出更确凿的结论。
