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乳腺癌保乳全乳切除术后同期植入与皮瓣技术用于乳房重建

Simultaneous Implant and Dermal Flap Technique for Breast Reconstruction After Skin-Sparing Total Mastectomy for Breast Carcinoma.

作者信息

Agdoğan Özgür, Gürdal Özkan Sibel

机构信息

Department of Plastic, Reconstructive and Aesthetic Surgery, Tekirdag Namik Kemal University, Tekirdag, Turkey.

Department of General Surgery, Tekirdag Namik Kemal University, Tekirdag, Turkey.

出版信息

Breast Cancer (Dove Med Press). 2025 Jul 14;17:599-610. doi: 10.2147/BCTT.S524455. eCollection 2025.

DOI:10.2147/BCTT.S524455
PMID:40686519
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12274270/
Abstract

OBJECTIVE

This study aims to evaluate the simultaneous implant and dermal flap technique for breast reconstruction following skin-sparing total mastectomy in breast carcinoma patients, assessing both oncological and aesthetic outcomes.

METHODS

A retrospective analysis was conducted on 28 patients who underwent skin-sparing total mastectomy with preservation of the nipple-areola complex, followed by immediate breast reconstruction using implants and dermal flaps. Data on patient demographics, surgical outcomes, complications, and patient satisfaction were collected and analyzed.

RESULTS

The study included 28 patients with an average age of 54.3 years. The implant sizes used ranged from 200 to 325 cc. Among these patients, 7 were chronic smokers and 8 had chronic diseases. A total of 22 patients underwent bilateral mastectomies, while 6 had unilateral mastectomies. Axillary lymph node dissection was performed in all cases. Preoperative radiotherapy was administered to 3 patients, and postoperative radiotherapy was given to 5 patients. Two patients experienced unilateral complete necrosis of the NAC and skin, while one patient had partial NAC necrosis. No evidence of capsular contracture, tumor recurrence, or metastasis was observed during the follow-up period. Patient satisfaction was high, with 24 out of 28 patients expressing positive outcomes.

CONCLUSION

Simultaneous implant and dermal flap breast reconstruction after skin-sparing total mastectomy offers a viable single-session approach with optimal cosmetic results, minimal morbidity, and high patient satisfaction. This technique is particularly beneficial for patients seeking immediate reconstruction with preserved nipple-areola complex.

摘要

目的

本研究旨在评估乳腺癌患者保乳全乳房切除术后同期植入物和真皮瓣乳房重建技术,评估肿瘤学和美学效果。

方法

对28例行保乳全乳房切除术并保留乳头乳晕复合体,随后立即采用植入物和真皮瓣进行乳房重建的患者进行回顾性分析。收集并分析患者人口统计学、手术结果、并发症和患者满意度的数据。

结果

该研究纳入28例患者,平均年龄54.3岁。使用的植入物大小范围为200至325cc。这些患者中,7例为长期吸烟者,8例患有慢性病。共有22例患者接受了双侧乳房切除术,6例接受了单侧乳房切除术。所有病例均进行了腋窝淋巴结清扫。3例患者接受了术前放疗,5例患者接受了术后放疗。2例患者出现乳头乳晕复合体和皮肤单侧完全坏死,1例患者出现乳头乳晕复合体部分坏死。随访期间未观察到包膜挛缩、肿瘤复发或转移的证据。患者满意度较高,28例患者中有24例表示结果良好。

结论

保乳全乳房切除术后同期植入物和真皮瓣乳房重建提供了一种可行的单阶段方法,具有最佳的美容效果、最小的发病率和较高的患者满意度。该技术对寻求保留乳头乳晕复合体的即刻重建的患者特别有益。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae84/12274270/751aa7d895a4/BCTT-17-599-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae84/12274270/35da560d54c9/BCTT-17-599-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae84/12274270/b3a904ce55eb/BCTT-17-599-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae84/12274270/dd0379e996b8/BCTT-17-599-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae84/12274270/b83558829f40/BCTT-17-599-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae84/12274270/751aa7d895a4/BCTT-17-599-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae84/12274270/35da560d54c9/BCTT-17-599-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae84/12274270/b3a904ce55eb/BCTT-17-599-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae84/12274270/dd0379e996b8/BCTT-17-599-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae84/12274270/b83558829f40/BCTT-17-599-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae84/12274270/751aa7d895a4/BCTT-17-599-g0005.jpg

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本文引用的文献

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Immediate Breast Reconstruction: Comparative Outcome Study of One-Stage Direct-to-Implant and Two-Stage/Tissue Expander Techniques.即刻乳房重建:一期直接植入式与二期/组织扩张器技术的比较结果研究
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Dual Coverage of the Inferior Pole with Conjoined Fascial Flap and Acellular Dermal Matrix for Immediate One-Stage Breast Reconstruction with a Prosthetic Implant.联合筋膜瓣和脱细胞真皮基质对乳房下极进行双重覆盖用于假体植入一期即刻乳房重建
Aesthetic Plast Surg. 2018 Oct;42(5):1213-1219. doi: 10.1007/s00266-018-1138-6. Epub 2018 Apr 17.
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Single-Stage Breast Reconstruction Using an All-In-One Adjustable Expander/Implant.
使用一体化可调节扩张器/植入物进行单阶段乳房重建。
Plast Reconstr Surg Glob Open. 2018 Jan 11;6(1):e1609. doi: 10.1097/GOX.0000000000001609. eCollection 2018 Jan.
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One-Stage Immediate Breast Reconstruction: A Concise Review.一期即刻乳房重建:简要综述。
Biomed Res Int. 2017;2017:6486859. doi: 10.1155/2017/6486859. Epub 2017 Oct 2.
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Acellular Dermal Matrix in Immediate Expander/Implant Breast Reconstruction: A Multicenter Assessment of Risks and Benefits.即时扩张器/植入物乳房重建中脱细胞真皮基质的多中心风险与效益评估
Plast Reconstr Surg. 2017 Dec;140(6):1091-1100. doi: 10.1097/PRS.0000000000003842.
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Treatment of Implant Exposure due to Skin Necroses after Skin Sparing Mastectomy: Initial Experiences Using a Not Selective Random Epigastric Flap.保留皮肤乳房切除术后皮肤坏死所致植入物外露的治疗:使用非选择性随机上腹皮瓣的初步经验
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