Black E R
Department of Medicine, University of Rochester School of Medicine and Dentistry, New York.
Prim Care. 1989 Mar;16(1):49-62.
Hypertension increases the incidence of adverse cardiovascular events such as stroke, heart failure, and coronary artery disease. Studies have shown that treatment of even mild hypertension can reduce the occurrence of these adverse cardiovascular events--particularly stroke, congestive heart failure, and progression to more severe hypertension. Patients with newly diagnosed hypertension can be treated pharmacologically with thiazide-type diuretics, beta-blockers, angiotensin-converting enzyme inhibitors, or calcium channel blockers. Nonpharmacologic therapy such as weight reduction can also play an important role in treatment. Additional study is needed to identify optimal drug treatment regimens and to clarify the association between treatment of hypertension and the occurrence of adverse effects from ischemic heart disease.
高血压会增加中风、心力衰竭和冠状动脉疾病等不良心血管事件的发生率。研究表明，即使是轻度高血压的治疗也可以减少这些不良心血管事件的发生——尤其是中风、充血性心力衰竭以及进展为更严重的高血压。新诊断的高血压患者可以使用噻嗪类利尿剂、β受体阻滞剂、血管紧张素转换酶抑制剂或钙通道阻滞剂进行药物治疗。非药物治疗，如减重，在治疗中也可发挥重要作用。需要进一步研究以确定最佳药物治疗方案，并阐明高血压治疗与缺血性心脏病不良反应发生之间的关联。
