Xiao Shuao, Feng Fan, Sun Li, Xu Guanghui, Lian Xiao, Guo Man, Nai Chao, Liu Zhen, Liu Shushang, Zhang Lei, Cai Lei, Liu Jinqiang, Zhang Hongwei
Department One of Digestive Diseases, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032, China.
Zhonghua Wei Chang Wai Ke Za Zhi. 2015 Oct;18(10):1011-5.
To investigate the relationship of ABO blood group with the clinicopathological characteristics in patients with gastric cancer and to assess whether the ABO blood group was associated with prognosis.
Clinicopathological and follow-up data of 2838 patients with gastric cancer who underwent radical gastrectomy in our department from June 2008 to October 2013 were analyzed retrospectively. The distribution of ABO blood group under different clinicopathological characteristics and the overall 5-year survival of ABO blood group were compared.
There were no significant differences in clinicopathological characteristics among patients with different ABO blood groups (all P>0.05). The 5-year overall survival(OS) rates were 57.3% for patients with blood type A, 54.7% for type B, 57.4% for type O, and 53.5% for type AB. Though there was no significance difference of survival among ABO blood groups(P=0.722), while the subgroup analysis indicated that stage III( patients of blood group Non-AB had a poorer OS compared to those of blood group AB(25.2% vs. 44.7%, P=0.014); smoking patients of blood group Non-AB had a poorer OS compared to those of blood group AB(53.4% vs. 74.9%, P=0.044).
Neither clinicopathological characteristics nor overall survival are associated with the ABO blood group, however, stage III( and smoking patients of blood group Non-AB have a poorer OS compared to those of blood group AB.
探讨ABO血型与胃癌患者临床病理特征的关系，并评估ABO血型是否与预后相关。
回顾性分析2008年6月至2013年10月在我科接受根治性胃切除术的2838例胃癌患者的临床病理及随访资料。比较不同临床病理特征下ABO血型的分布及ABO血型的总体5年生存率。
不同ABO血型患者的临床病理特征无显著差异（均P>0.05）。A型血患者的5年总生存率（OS）为57.3%，B型血为54.7%，O型血为57.4%，AB型血为53.5%。虽然ABO血型之间的生存率无显著差异（P=0.722），但亚组分析表明，Ⅲ期非AB血型患者的OS较AB血型患者差（25.2%对44.7%，P=0.014）；非AB血型吸烟患者的OS较AB血型患者差（53.4%对74.9%，P=0.044）。
临床病理特征和总生存率均与ABO血型无关，然而，Ⅲ期及非AB血型吸烟患者的OS较AB血型患者差。
