Le Saux N, Ronald A R
Department of Medicine, University of Manitoba, Winnipeg, Canada.
Rev Infect Dis. 1989 Mar-Apr;11(2):299-309. doi: 10.1093/clinids/11.2.299.
Ceftriaxone is a third-generation cephalosporin with antibacterial and pharmacokinetic characteristics that make it an excellent choice for the treatment of gonococcal infection and chancroid. Adverse effects are unusual. Clinical efficacy in all reported studies has been excellent. Additional studies are required for further elucidation of the role of ceftriaxone in the treatment of pelvic inflammatory disease and syphilis. Chlamydial infections are not altered by ceftriaxone, and additional treatment is necessary if Chlamydia is present concurrently with Neisseria gonorrhoeae.
头孢曲松是一种第三代头孢菌素，具有抗菌和药代动力学特性，使其成为治疗淋菌性感染和软下疳的理想选择。不良反应罕见。在所有已报道的研究中，临床疗效均极佳。需要进一步开展研究以阐明头孢曲松在治疗盆腔炎和梅毒中的作用。头孢曲松对衣原体感染无效，如果衣原体与淋病奈瑟菌同时存在，则需要额外治疗。
