Carlsson P
Department of Cariology, Faculty of Odontology, Lund University, Malmö, Sweden.
Scand J Dent Res. 1989 Apr;97(2):120-5. doi: 10.1111/j.1600-0722.1989.tb01440.x.
The observations in the Vipeholm Study regarding sugar consumption and oral lactobacillus counts were reviewed in relation to recent data on the epidemiology of mutans streptococci. The mutans streptococci were not present in higher counts in a population with high level of sugar consumption compared to two populations with a low level. As expected, differences were found in the caries prevalence between the different populations. An association between bacterial count and dental caries status could be demonstrated at the low level of sugar consumption and caries prevalence. Strains of mutans streptococci isolated in a population with extremely low caries prevalence were shown to be cariogenic in the hamster model. It is apparent that the observations made in the Vipeholm Study and the present finding have similarities, although different bacteria are studied. It was concluded that the difference in diet between the populations or groups were not sufficient to affect the counts of lactobacilli or mutans streptococci, but may have been sufficient to create the differences in caries prevalence.
结合近期关于变形链球菌流行病学的数据，对维佩霍尔姆研究中有关糖消耗与口腔乳酸杆菌计数的观察结果进行了回顾。与两个低水平糖消耗人群相比，高糖消耗人群中变形链球菌的数量并未更高。正如预期的那样，不同人群之间的龋齿患病率存在差异。在低糖消耗和低龋齿患病率水平下，可以证明细菌计数与龋齿状况之间存在关联。在龋齿患病率极低的人群中分离出的变形链球菌菌株，在仓鼠模型中显示具有致龋性。显然，尽管研究的是不同细菌，但维佩霍尔姆研究中的观察结果与目前的发现有相似之处。得出的结论是，人群或组之间的饮食差异不足以影响乳酸杆菌或变形链球菌的计数，但可能足以造成龋齿患病率的差异。
