Tomkins-Netzer Oren, Talat Lazha, Ismetova Filis, Samy Ahmed, Lightman Susan
Dev Ophthalmol. 2016;55:265-75. doi: 10.1159/000431202. Epub 2015 Oct 26.
Corticosteroids are the cornerstone of treating intraocular inflammation, but may be inadequate in controlling the disease, or related side effects preclude long-term treatment. Additional immunosuppressive drugs are used in these cases to augment the effect of corticosteroids and allow for their reduction to safe levels while maintaining control of the ocular inflammation. Here we review the different classes of immunosuppressive drugs and discuss their effect on ocular inflammation.
皮质类固醇是治疗眼内炎症的基石,但在控制疾病方面可能并不充分,或者相关副作用使长期治疗受到限制。在这些情况下,会使用其他免疫抑制药物来增强皮质类固醇的效果,并在维持眼部炎症控制的同时,使其减少到安全水平。在此,我们综述不同类别的免疫抑制药物,并讨论它们对眼部炎症的作用。