Shah-Desai Sabrina, Azarbod Parham, Szamocki Sonia, Rose Geoffrey E
*Barking Havering Redbridge University Hospitals NHS Trust, Essex, England; and †Moorfields Eye Hospital, London, United Kingdom.
Ophthalmic Plast Reconstr Surg. 2016 Jan-Feb;32(1):61-4. doi: 10.1097/IOP.0000000000000576.
Repair of blepharoptosis secondary to surgical overcorrection of thyroid related primary upper eyelid retraction (secondary ptosis) can be unpredictable. This study describes the long-term results of "hang-back" nylon sutures, for an anterior approach surgical repair of secondary ptosis.
This was a retrospective consecutive case note review of patients referred with secondary ptosis (after prior upper eyelid lowering for thyroid eye disease), under the care of a single surgeon at Moorfields Eye Hospital & subsequently at Barking Havering Redbridge University Hospitals NHS Trust (SSD). In accordance with hospital trust policy, this audit was registered and all patient data was anonymized, ethical approval was not required. Patients with secondary ptosis underwent surgery under local anesthesia through an upper eyelid skin-crease incision. The anterior portion of the levator muscle was freed from all scar tissues and its action re-established on the superior part of the upper tarsal plate, using two 6-0 nylon hang-back sutures placed centrally and medially. The margin reflex distance 1 (MRD1), skin crease height, eyelid contour, symmetry of eyelid position (difference in margin reflex distance 1 <1 mm in both eyes) and degree of lagophthalmos were assessed from clinical notes preoperative and postoperatively at 1, 3, and 12 months.
Surgery was undertaken in 14 eyelids in 13 patients (3 males; 23%), with 9/14 (65%) eyelids having undergone attempted repair of ptosis prior to referral; in 7 of the 8 (88%) eyelids with previous failed ptosis repair, the referring surgeon had used soluble hang-back sutures. As compared with an average preoperative margin reflex distance 1 of 0.9 mm (median 1, range: -1 to 2 mm), the average margin reflex distance 1 at 3 months was 3.0 mm (median 3, range: 2.5-4 mm; p < 0.0001) and 2.8 mm at 12-month follow up (median 3, range: 2-4mm; p < 0.0001). The upper eyelid central skin crease height changed from a preoperative mean of 9.8 mm (median 9, range: 5-15 mm) to 8.7 mm at 3 months (median 8, range: 7-12 mm; p = 0.1412) and 8.9 mm at 12-month follow up (median 9, range: 7-11 mm; p = 0.2930). Only 3 patients had postoperative lagophthalmos (one patient 3 mm and two patients 1 mm) at 3 months after surgery, this resolving by the 12-month postoperative visit. Thirteen cases (93%) had a good functional, symmetrical, and aesthetic result at 12 month follow up, with a late recurrence of ptosis in 1 patient (7%).
The "hang-back" semi-permanent suture technique for repair of over-corrected upper eyelid lowering in thyroid eye disease appears to provide an excellent and predictable long-term result with a low incidence of late recurrence of ptosis.
修复因甲状腺相关原发性上睑退缩手术过度矫正继发的上睑下垂(继发性上睑下垂)可能具有不可预测性。本研究描述了“悬吊”尼龙缝线用于前路手术修复继发性上睑下垂的长期效果。
这是一项对在摩尔菲尔德眼科医院及随后在巴金哈弗灵雷德布里奇大学医院国民保健服务信托基金(SSD)由同一位外科医生诊治的继发性上睑下垂患者(先前因甲状腺眼病行上睑下垂矫正术后)的回顾性连续病例记录研究。根据医院信托政策,此次审核已登记,所有患者数据均已匿名,无需伦理批准。继发性上睑下垂患者在局部麻醉下通过上睑皮肤皱襞切口进行手术。提上睑肌前部从所有瘢痕组织中游离出来,并通过在中央和内侧放置两根6-0尼龙悬吊缝线,使其对上睑板上部的作用得以重建。术前及术后1、3和12个月从临床记录中评估边缘反射距离1(MRD1)、皮肤皱襞高度、眼睑轮廓、眼睑位置对称性(双眼边缘反射距离1差异<1mm)及眼球突出程度。
13例患者的14只眼睑接受了手术(3例男性;23%),其中9/14(65%)只眼睑在转诊前曾尝试修复上睑下垂;在8例先前上睑下垂修复失败的眼睑中,有7例(88%)转诊医生使用了可溶解的悬吊缝线。与术前平均边缘反射距离1为0.9mm(中位数1,范围:-1至2mm)相比,术后3个月平均边缘反射距离1为3.0mm(中位数3,范围:2.5 - 4mm;p < 0.0001),12个月随访时为2.8mm(中位数3,范围:2 - 4mm;p < 0.0001)。上睑中央皮肤皱襞高度从术前平均9.8mm(中位数9,范围:5 - 15mm)变为术后3个月的8.7mm(中位数8,范围:7 - 12mm;p = 0.1412)和12个月随访时的8.9mm(中位数9,范围:7 - 11mm;p = 0.2930)。术后仅3例患者在术后3个月出现眼球突出(1例患者3mm,2例患者1mm),在术后12个月复诊时消失。13例(93%)在12个月随访时功能、对称及美观效果良好,1例患者(7%)上睑下垂晚期复发。
“悬吊”半永久性缝线技术用于修复甲状腺眼病中过度矫正的上睑下垂,似乎能提供优异且可预测的长期效果,上睑下垂晚期复发率低。