Corneoplastic Unit, Queen Victoria Hospital NHS Foundation Trust, East Grinstead, West Sussex, UK.
Eye (Lond). 2011 Feb;25(2):185-91. doi: 10.1038/eye.2010.177. Epub 2010 Nov 19.
To describe the pre- and postoperative features of the visible iris sign (VIS), which is the apparent visibility of iris colour through a closed upper eyelid, in patients undergoing anterior approach surgery for severe involutional aponeurotic ptosis, and to assess its effect on postoperative outcome.
Prospective, comparative interventional case series.
Prospective series of all patients undergoing surgery for severe involutional aponeurotic ptosis during a 16-month period at a single centre.
Severe involutional ptosis (upper eyelid margin reflex distance (MRD) ≤1 mm) treated by anterior-approach surgery.
Presence of VIS, type of ptosis (primary or recurrent), preoperative MRD, levator function and skin crease height, documented unusual intra-operative findings, postoperative complications, and follow-up time.
Of 133 procedures for involutional aponeurotic ptosis, 96 procedures (56 patients) were included in the study. In total, 12 patients (21%, 12/56, 2 males, and 10 females) had been identified as having VIS preoperatively. In order to avoid any selection bias, only patients with severe degree of ptosis were included in the two groups with the two groups being alike in the preoperative lid height, levator function or the skin crease. In the VIS group, 55% (12/22) had a thinned, significantly retracted levator aponeurosis and a thin tarsus prone to full-thickness suture passes (36.3%, 8/22) during aponeurosis reattachment. Immediate persistent overcorrection during surgery was seen in three procedures, with one patient having an under corrected outcome when treated with a hang-back suture. In the non-VIS group, no patients were documented intra-operatively, as having significant retraction of the levator aponeurosis. However, 14% (10/74) of the eyelids were recorded as having a very attenuated levator and one patient (3%, 1/44) was noted to have a floppy tarsus that was difficult to suture. The total incidence of intra-operative difficulties during surgery were 78% in the VIS group and 22% in the non-VIS group. Mean postoperative follow-up was 22 weeks. (median 18, range 12-64). The overall success rates were 63.6% (14/22) in the VIS group, compared with 77.0% (57/74) in the non-VIS group (P = 0.260). After excluding cases undergoing concurrent blepharoplasty and non-Caucasians, success rates were 57.1% (4/7) and 69.2% (9/13) in the VIS and non-VIS groups, respectively (P = 0.598). All failures were because of under-correction.
The VIS is a clinical sign of severe involutional ptosis. Patients with VIS have one or more features, including a retracted levator aponeurosis, a thinned tarsus prone to full-thickness suture passes, and a tendency for immediate persistent overcorrection following levator advancement. Preoperative identification of VIS may help in appropriate patient counselling, procedure selection, anticipation of intraoperative difficulties, and possibly further standardisation of future cohorts when evaluating the results of involutional ptosis surgery. PRÉCIS: The authors describe the pre-, intra- and postoperative features of visible iris sign. They discuss the success rates of anterior approach surgery in VIS patients and discuss the contributing factors for a poorer outcome.
描述严重退行性腱膜性上睑下垂患者行前路手术时,可见虹膜征(VIS)的术前和术后特征,即通过闭合的上眼睑可以明显看到虹膜颜色,评估其对术后结果的影响。
前瞻性、对照干预性病例系列研究。
在单中心进行的为期 16 个月的严重退行性腱膜性上睑下垂患者前路手术的前瞻性系列研究。
严重退行性上睑下垂(上睑缘反射距离(MRD)≤1mm),行前路手术治疗。
VIS 的存在、上睑下垂的类型(原发性或复发性)、术前 MRD、提上睑肌功能和皮肤折痕高度、记录术中异常发现、术后并发症和随访时间。
在 133 例退行性腱膜性上睑下垂手术中,96 例(56 例患者)纳入研究。共有 12 例(21%,12/56,2 例男性,10 例女性)患者术前被诊断为 VIS。为了避免任何选择偏倚,仅纳入严重程度的上睑下垂患者,两组患者术前眼睑高度、提上睑肌功能或皮肤折痕相似。在 VIS 组中,55%(12/22)的患者提上睑肌腱膜明显变薄、回缩,上睑提肌薄弱,容易进行全层缝线穿过(36.3%,8/22)。在进行腱膜再附着时,有 3 例手术中出现即刻持续过矫,1 例患者行 Hang-back 缝线时出现矫正不足。在非 VIS 组中,术中没有患者被记录为明显的提上睑肌腱膜回缩。然而,14%(10/74)的眼睑被记录为提上睑肌非常薄弱,1 例(3%,1/44)患者的睑板薄弱,难以缝合。VIS 组术中困难的总发生率为 78%,非 VIS 组为 22%。平均术后随访 22 周(中位数 18 周,范围 12-64 周)。VIS 组的总成功率为 63.6%(14/22),而非 VIS 组为 77.0%(57/74)(P=0.260)。排除同期行重睑成形术和非白种人的患者后,VIS 组和非 VIS 组的成功率分别为 57.1%(4/7)和 69.2%(9/13)(P=0.598)。所有失败病例均为矫正不足。
VIS 是严重退行性上睑下垂的一种临床特征。VIS 患者存在一种或多种特征,包括提上睑肌腱膜回缩、上睑板薄弱容易进行全层缝线穿过以及提上睑肌前移后即刻持续过矫的倾向。术前识别 VIS 有助于对患者进行适当的咨询、选择合适的手术方法、预测术中困难,并在评估退行性上睑下垂手术结果时,可能有助于进一步对未来队列进行标准化。