Loeper J, Debray J, Cottet J, Loeper J
Nouv Presse Med. 1977 Feb 19;6(7):539-43.
The determination of blood amino-acids by column chromatography has been carried out on 53 patients, 17 with acute myeloid leukemia, 22 with chronic myeloid leukemia. A comparison was made with 25 normal subjects. These determination has shown a significant increase in glycin, cystin and a non significant increase of tryptophan. A positive relationship may exist between uricemia and content of glycin and glutamin, both amino-acids which are messengers of uric acid. A positive correlation has been found between glycin tryptophan and the number of myeloblasts.
已对53例患者进行了柱色谱法测定血氨基酸,其中17例为急性髓性白血病患者,22例为慢性髓性白血病患者。并与25名正常受试者进行了比较。这些测定结果显示,甘氨酸、胱氨酸显著增加,色氨酸有不显著增加。尿酸血症与甘氨酸和谷氨酰胺含量之间可能存在正相关关系,这两种氨基酸都是尿酸的信使。已发现甘氨酸、色氨酸与成髓细胞数量之间存在正相关。