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C 反应蛋白和白细胞计数单独检测能否排除急性腹痛的急腹症?

Can C-reactive protein and white blood cell count alone rule out an urgent condition in acute abdominal pain?

机构信息

SOC Medicina d'Urgenza e Pronto Soccorso AOU S. Maria della Misericordia, Udine, UD, Italy.

出版信息

Intern Emerg Med. 2016 Feb;11(1):141-2. doi: 10.1007/s11739-015-1333-2. Epub 2015 Oct 27.

DOI:10.1007/s11739-015-1333-2
PMID:26506830
Abstract

Up to 10% of all patients at the Emergency Department present for acute abdominal pain. The C-reactive protein (CRP) and white blood cell (WBC) are routinely determined as part of the workup of patients with abdominal pain. Three large prospective cohort studies comprising a total of 2961 adult patients with acute abdominal pain were selected. CRP levels and WBC counts were compared between patients with urgent and nonurgent final diagnoses. These studies conclude that the laboratory values individually are weak discriminators and cannot be used as a triage instrument in the selection of patients with acute abdominal pain requiring additional diagnostic tests.

摘要

多达 10%的急诊科患者因急性腹痛就诊。作为腹痛患者检查的一部分,通常会测定 C 反应蛋白(CRP)和白细胞(WBC)。选择了三项包含总共 2961 例急性腹痛成年患者的大型前瞻性队列研究。比较了急危诊断和非急危诊断患者的 CRP 水平和 WBC 计数。这些研究表明,实验室值单独作为鉴别诊断指标的能力较弱,不能作为急性腹痛患者选择是否需要进一步诊断性检查的分诊工具。

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本文引用的文献

1
C-reactive protein and white blood cell count as triage test between urgent and nonurgent conditions in 2961 patients with acute abdominal pain.C反应蛋白和白细胞计数作为2961例急性腹痛患者区分紧急与非紧急情况的分诊检查。
Medicine (Baltimore). 2015 Mar;94(9):e569. doi: 10.1097/MD.0000000000000569.
2
Guideline for the diagnostic pathway in patients with acute abdominal pain.急性腹痛患者诊断路径指南。
Dig Surg. 2015;32(1):23-31. doi: 10.1159/000371583. Epub 2015 Jan 28.
3
Imaging strategies for detection of urgent conditions in patients with acute abdominal pain: diagnostic accuracy study.
急性腹痛患者紧急情况检测的影像学策略:诊断准确性研究。
BMJ. 2009 Jun 26;338:b2431. doi: 10.1136/bmj.b2431.