Shih Han, Mirmira Raghavendra G, Lin Chien-Chi
Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, USA.
Departments of Pediatrics, Medicine, Cellular and Integrative Physiology, and Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, USA.
J Mater Chem B. 2015;3(2):170-175. doi: 10.1039/C4TB01593B.
A cytocompatible visible light-mediated interfacial thiol-norbornene photopolymerization scheme was developed for creating hydrogel conformal coating on pancreatic islets. The step-growth thiol-norbornene reaction affords high consistency and tunability in gel coating thickness. Furthermore, isolated islets coated with thiol-norbornene gel maintained their viability and function .
开发了一种细胞相容性可见光介导的界面硫醇-降冰片烯光聚合方案,用于在胰岛上创建水凝胶保形涂层。逐步增长的硫醇-降冰片烯反应在凝胶涂层厚度方面提供了高度的一致性和可调性。此外,涂有硫醇-降冰片烯凝胶的分离胰岛保持了它们的活力和功能。