Pituch-Zdanowska Aleksandra, Banaszkiewicz Aleksandra, Albrecht Piotr
Department of Paediatric Gastroenterology and Nutrition, Medical University of Warsaw, Warsaw, Poland.
Prz Gastroenterol. 2015;10(3):135-41. doi: 10.5114/pg.2015.52753. Epub 2015 Jul 15.
The aetiology of inflammatory bowel diseases (IBD), which are primarily Crohn's disease and ulcerative colitis, still remains unclear, while the incidence of IBD is constantly increasing, especially in the industrialised countries. Among genetic, environmental, and immunological factors, changes in the composition of the intestinal microflora and diet are indicated as very important in initiating and sustaining inflammation in patients with IBD. Above all nutrients dietary fibre is an especially important component of diet in the context of IBD. A potentially protective effect of high-fibre diet on intestinal disorders was described as early as in 1973. Several trials performed in animal models of IBD and human studies have reported that supplementation of some types of dietary fibre can prolong remission and reduce lesions of the intestinal mucosa during the course of the disease. This paper presents the current state of knowledge on the effects of dietary fibre in IBD.
炎症性肠病（IBD）主要包括克罗恩病和溃疡性结肠炎，其病因仍不明确，而IBD的发病率却在不断上升，尤其是在工业化国家。在遗传、环境和免疫因素中，肠道微生物群组成的变化和饮食被认为在IBD患者炎症的起始和持续过程中非常重要。在所有营养素中，膳食纤维在IBD背景下是饮食中尤为重要的组成部分。早在1973年就有人描述了高纤维饮食对肠道疾病的潜在保护作用。在IBD动物模型中进行的多项试验以及人体研究报告称，补充某些类型的膳食纤维可以延长缓解期，并减少疾病过程中肠黏膜的损伤。本文介绍了关于膳食纤维对IBD影响的当前知识状况。
