Coskun Adil, Yavasoglu Irfan, Sargin Gokhan, Ok Ismail Murat, Bircan Metin, Avcil Mucahit, Kadikoylu Gurhan, Bolaman Zahit
Division of Gastroenterology, Medical Faculty, Adnan Menderes University, Aydin, Turkey.
Division of Haematology, Medical Faculty, Adnan Menderes University, Aydin, Turkey.
Prz Gastroenterol. 2015;10(3):156-9. doi: 10.5114/pg.2015.49042. Epub 2015 Feb 10.
Platelets play an important role in inflammation. Mean platelet volume (MPV) may be a useful parameter for inflammatory conditions, in differentiating between non-specific abdominal pain (NSAP) and conditions requiring surgery, or early diagnosis of abdominal pain as a serious problem for emergency services.
To investigate the role of MPV on NSAP admittance to the emergency department.
The study consisted of 330 patients (186 female and 144 male, with mean age 49 ±20 years) with NSAP and 249 patients with abdominal pain (144 female and 105 male, with mean age 49 ±19 years) applied to our emergency service and enrolled to our study. Medical history, physical examination, complete blood count (CBC), and biochemical parameters were evaluated. Haematological parameters were measured by Beckman Coulter LH 780 instrument. Data were compared using Student's t test, and p < 0.05 was accepted as statistically significant.
The MPV were significantly lower in patients with NSAP than in others (p = 0.025). There was no significant difference between both sexes with regard to MPV (p > 0.05). Moreover, the other haematological parameters (haemoglobin, platelet, or WBC counts) were not statistically different between both groups (p > 0.05).
The MPV may be a useful, simple, and inexpensive parameter to diagnose or differentiate between NSAP and other conditions.
血小板在炎症中发挥着重要作用。平均血小板体积（MPV）可能是炎症性疾病的一个有用参数，可用于区分非特异性腹痛（NSAP）和需要手术的疾病，或作为急诊科将腹痛早期诊断为严重问题的一个指标。
研究MPV在NSAP患者急诊入院中的作用。
本研究纳入了330例NSAP患者（186例女性，144例男性，平均年龄49±20岁）和249例腹痛患者（144例女性，105例男性，平均年龄49±19岁），这些患者均到我院急诊科就诊并纳入本研究。对患者的病史、体格检查、全血细胞计数（CBC）和生化参数进行评估。血液学参数通过贝克曼库尔特LH 780仪器进行测量。采用Student's t检验对数据进行比较，p<0.05被认为具有统计学意义。
NSAP患者的MPV显著低于其他患者（p = 0.025）。MPV在两性之间无显著差异（p>0.05）。此外，两组间其他血液学参数（血红蛋白、血小板或白细胞计数）无统计学差异（p>0.05）。
MPV可能是诊断或区分NSAP与其他疾病的一个有用、简单且廉价的参数。
