Sokolowska-Köhler W, Bollmann R, Mehl M, Starke R, Presber W
Institut für Medizinische Mikrobiologie, Bereich Medizin (Charité) der Humboldt-Universität, Berlin, DDR.
J Basic Microbiol. 1989;29(1):49-54. doi: 10.1002/jobm.3620290113.
The influence of two different types of Escherichia coli K1 capsule preparation on the phagosytosis of an E. coli laboratory strain (LN 28) by polymorphnuclear leucocytes (PMNL) is described. Capsule material of E. coli 0.18 and 0.83 was prepared a) from the culture supernatant and b) from a bacterial pellet fraction. When capsule material from the pellet was added to opsonin, before mixing the laboratory strain with the PMNL, it decreased the rate of phagocytosis, compared with untreated opsonin. The preparation from the supernatant of capsule showed no alteration of phagocytosic rate or capacity. These results are explained by the different chemical compositions of the preparations.
本文描述了两种不同类型的大肠杆菌K1荚膜制剂对多形核白细胞（PMNL）吞噬大肠杆菌实验室菌株（LN 28）的影响。大肠杆菌0.18和0.83的荚膜材料分别通过以下两种方式制备：a）从培养上清液中制备；b）从细菌沉淀部分制备。当在将实验室菌株与PMNL混合之前，将来自沉淀的荚膜材料添加到调理素中时，与未处理的调理素相比，吞噬率降低。来自荚膜上清液的制剂未显示吞噬率或吞噬能力的改变。这些结果可以通过制剂的不同化学成分来解释。
