Alhan Canan, Westers Theresia M, Cremers Eline M P, Cali Claudia, Ossenkoppele Gert J, van de Loosdrecht Arjan A
Department of Hematology, Cancer Center Amsterdam (CCA), VU University Medical Center, Amsterdam, The Netherlands.
Cytometry B Clin Cytom. 2016 Jul;90(4):358-67. doi: 10.1002/cyto.b.21333. Epub 2015 Dec 14.
The application of flow cytometry (FC) is recommended as part of the diagnostic approach for MDS. The complexity of flow cytometric analysis of bone marrow cells in MDS has been an obstacle for general application. However, in the past years several studies showed practical flow cytometric approaches for the diagnosis and prognosis of MDS. In this report we discuss technical considerations and highlight issues that require special attention when handling and analyzing bone marrow samples of patients with cytopenia and suspicion of MDS. © 2015 Clinical Cytometry Society.
推荐将流式细胞术（FC）的应用作为骨髓增生异常综合征（MDS）诊断方法的一部分。MDS中骨髓细胞流式细胞术分析的复杂性一直是其广泛应用的障碍。然而，在过去几年中，多项研究展示了用于MDS诊断和预后评估的实用流式细胞术方法。在本报告中，我们讨论技术要点，并强调在处理和分析血细胞减少且怀疑患有MDS患者的骨髓样本时需要特别关注的问题。© 2015临床细胞计量学会
