Gaudino Mario, Glineur David, Mazza Andrea, Papadatos Spiridon, Farina Piero, Etienne Pierre Yves, Fracassi Francesco, Cammertoni Federico, Crea Filippo, Massetti Massimo
Division of Cardiac Surgery, Catholic University, Rome, Italy.
Department of Cardiology, Université Catholique de Louvain, Mongodinne.
Ann Thorac Surg. 2016 Mar;101(3):960-6. doi: 10.1016/j.athoracsur.2015.08.066. Epub 2015 Oct 28.
This study evaluated the long-term outcome of patients undergoing emergency coronary artery bypass grafting (eCABG) for cardiogenic shock after acute myocardial infarction.
Sixty-seven consecutive patients underwent eCABG for cardiogenic shock at 2 European institutions during an 11-year period. Preoperative, intraoperative, postoperative, and long-term follow-up data of all patients were prospectively collected.
Hospital survival was 86% (58 of 67), with all deaths due to cardiac causes. At a mean follow-up of 78 ± 48 months (range, 1 to 153 months), 43 of the 58 patients (74%) discharged from the hospital were alive. Causes of death in 9 of the 15 follow-up deaths (60%) were noncardiac. Overall survival rate at the end of follow-up was 64% (43 of 67). Of the 43 survivors, 41 (95%) were in New York Heart Association Functional Classification I to II, ischemia free, had a Karnofsky performance status exceeding 80, and an excellent quality of life as assessed by the Seattle Angina Questionnaire. The use of cardiopulmonary bypass and the internal thoracic artery were associated with significantly better long-term survival.
The long-term survival and quality of life of patients who undergo eCABG for cardiogenic shock after acute myocardial infarction are good, and eCABG should be considered a valuable therapeutic option in this setting. The use of cardiopulmonary bypass and the internal thoracic artery at the time of the operation are strongly advocated.
本研究评估了急性心肌梗死后因心源性休克接受急诊冠状动脉旁路移植术(eCABG)患者的长期预后。
在11年期间,欧洲两家机构的67例连续患者因心源性休克接受了eCABG。前瞻性收集了所有患者的术前、术中、术后及长期随访数据。
医院生存率为86%(67例中的58例),所有死亡均由心脏原因导致。在平均随访78±48个月(范围1至153个月)时,58例出院患者中有43例(74%)存活。15例随访死亡患者中有9例(60%)的死亡原因是非心脏性的。随访结束时的总生存率为64%(67例中的43例)。在43例幸存者中,41例(95%)纽约心脏协会心功能分级为I至II级,无缺血,卡氏功能状态超过80,且根据西雅图心绞痛问卷评估生活质量良好。使用体外循环和胸廓内动脉与显著更好的长期生存相关。
急性心肌梗死后因心源性休克接受eCABG患者的长期生存和生活质量良好,在这种情况下eCABG应被视为一种有价值的治疗选择。强烈提倡在手术时使用体外循环和胸廓内动脉。