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急性心肌梗死后的急诊冠状动脉搭桥术

[Emergent coronary bypass grafting after acute myocardial infarction].

作者信息

Ozaki S, Toyama M, Ohashi T, Kawase I, Sekiguchi S, Horimi H

机构信息

Department of Cardiovascular Surgery, Kameda Medical Center, Chiba, Japan.

出版信息

Nihon Kyobu Geka Gakkai Zasshi. 1996 Nov;44(11):2000-5.

PMID:8958714
Abstract

In an attempt to examine various factors affecting the short- and long-term results of emergent coronary bypass graft surgery (ECABG) after an acute myocardial infarction (AMI), all patients undergoing ECABG without associated procedures at our institution from January 1987 to July 1995 were reviewed. Forty eight patients underwent ECABG after AMI. The hospital mortality rate was 20.8%. The charts of these patients were reviewed with regard to sex, age, preoperative shock, location of AMI, type of infarction, coronary anatomy, presence of postinfarction angina, technique of myocardial preservation, use of saphenous vein graft (SVG) alone, time from AMI to operation and short and long-term outcome. Univariate analyses showed that three factors were significantly associated with increased hospital death: preoperative shock (p = 0.001), type of infarction (p = 0.01), use of SVG alone (p = 0.003). Follow-up was 100% complete at a mean time of 36.4 +/- 4.8 months. Of all patients 77.0% were alive at 5 years after operation. Univariate comparison of survival curves and coronary event free curves showed that use of SVG alone was associated with decreased survival (p = 0.0009) and event free (p = 0.02) rates. Patients with non-Q-wave infarction and without cardiogenic shock may undergo ECABG relatively safely at any time. The use of internal thoracic artery at ECABG without cardiogenic shock does not increase hospital mortality and improves both long-term survival and freedom from coronary events.

摘要

为了研究影响急性心肌梗死(AMI)后急诊冠状动脉搭桥手术(ECABG)短期和长期结果的各种因素,我们回顾了1987年1月至1995年7月在我院接受无相关联合手术的ECABG的所有患者。48例患者在AMI后接受了ECABG。医院死亡率为20.8%。对这些患者的病历进行了回顾,内容包括性别、年龄、术前休克、AMI部位、梗死类型、冠状动脉解剖、梗死后心绞痛的存在、心肌保护技术、单纯使用大隐静脉移植血管(SVG)、从AMI到手术的时间以及短期和长期结果。单因素分析显示,三个因素与医院死亡增加显著相关:术前休克(p = 0.001)、梗死类型(p = 0.01)、单纯使用SVG(p = 0.003)。平均随访时间为36.4 +/- 4.8个月,随访完成率为100%。所有患者中,77.0%在术后5年存活。生存曲线和无冠状动脉事件曲线的单因素比较显示,单纯使用SVG与生存率降低(p = 0.0009)和无事件率降低(p = 0.02)相关。非Q波梗死且无心源性休克的患者可在任何时间相对安全地接受ECABG。在无心源性休克的ECABG中使用胸廓内动脉不会增加医院死亡率,并且可改善长期生存率和无冠状动脉事件发生率。

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