Schlichte Megan J, Talpur Rakhshandra, Venkatarajan Sangeetha, Curry Jonathan L, Nagarajan Priyadharsini, Duvic Madeleine
Baylor College of Medicine, Houston, TX, USA.
University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Int J Dermatol. 2016 Mar;55(3):e126-9. doi: 10.1111/ijd.13082. Epub 2015 Oct 30.
Mycosis fungoides is a potentially fatal skin condition whose variable clinical appearance may mimic a variety of benign, inflammatory dermatoses, making it a diagnostic challenge. Three patients with mycosis fungoides, treated with multiple approved topical and systemic therapies, presented with acquired verrucous lesions on the extremities. The verrucous presentation of mycosis fungoides is one of the many atypical forms of the disease, with a paucity of documented cases in the medical literature. Although rare, verrucous and hyperkeratotic lesions in mycosis fungoides may increase the risk of considerable diagnostic delay if clinicians do not maintain a high degree of suspicion in cases of acquired verrucous lesions in the appropriate clinical setting.
蕈样肉芽肿是一种潜在致命的皮肤疾病，其临床表现多样，可能酷似各种良性炎症性皮肤病，这使其成为一项诊断挑战。三名接受过多种获批的局部和全身治疗的蕈样肉芽肿患者，四肢出现了后天性疣状皮损。蕈样肉芽肿的疣状表现是该疾病众多非典型形式之一，医学文献中记载的病例较少。尽管罕见，但如果临床医生在适当的临床环境中对后天性疣状皮损病例没有保持高度怀疑，蕈样肉芽肿中的疣状和角化过度性皮损可能会增加显著诊断延迟的风险。
