Perlbarg J, Rabetrano H, Soulié M, Salomon L, Durand-Zaleski I
URC-Eco (unité de recherche clinique spécialisée en économie de la santé), Hôtel-Dieu, AP-HP, 1, place du Parvis-Notre-Dame, 75004 Paris, France.
Département d'urologie-andrologie-transplantation rénale, CHU Rangueil, 1, avenue Jean-Poulhès, 31059 Toulouse cedex 9, France.
Prog Urol. 2015 Nov;25(15):1108-15. doi: 10.1016/j.purol.2015.07.012.
Prostate cancer is the most frequent cancer and the third leading cause of cancer death in men in France. The development of treatment for prostate cancer is fast and sometimes relies on costly innovations. Medico-economic studies are however rare in this area. This literature review aims to summarize available medico-economic data on the initial management of localized prostate cancer and discuss the quality and usability of existing economic studies on the subject.
Literature review was done using PubMed and Cochrane databases. Studies and articles were selected based on several criteria: population with initial treatment for localized prostate cancer (without metastasis), comparative studies with surgery as control treatment, studies in countries members of the OECD, articles in English or French published between 2004 and 2014.
The surgical robot, one of the newest innovations, is more expensive than conventional open surgery or no robotic laparoscopy, even if it is associated with a reduction of the original period of stay. Radiation therapy seems more expensive than surgery as initial therapy of localized prostate cancer.
Conclusions remain limited because of the rarity of reliable health economic studies on the subject.
前列腺癌是法国男性中最常见的癌症，也是男性癌症死亡的第三大主要原因。前列腺癌治疗方法的发展迅速，有时依赖于成本高昂的创新。然而，该领域的医学经济学研究却很少。这篇文献综述旨在总结关于局限性前列腺癌初始治疗的现有医学经济学数据，并讨论该主题现有经济研究的质量和实用性。
使用PubMed和Cochrane数据库进行文献综述。根据以下几个标准选择研究和文章：接受局限性前列腺癌初始治疗（无转移）的人群、以手术作为对照治疗的比较研究、经合组织成员国的研究、2004年至2014年间发表的英文或法文文章。
最新的创新之一手术机器人比传统开放手术或非机器人腹腔镜手术更昂贵，即使它与缩短初始住院时间相关。放射治疗作为局限性前列腺癌的初始治疗似乎比手术更昂贵。
由于关于该主题的可靠健康经济研究很少，结论仍然有限。
