Mearin Fermín, Rey Enrique, Balboa Agustín
Servicio de Aparato Digestivo, Instituto de Trastornos Funcionales y Motores Digestivos, Centro Médico Teknon, Barcelona, España.
Servicio de Aparato Digestivo, Hospital Clínico Universitario San Carlos, Madrid, España.
Gastroenterol Hepatol. 2015 Sep;38 Suppl 1:3-12. doi: 10.1016/S0210-5705(15)30014-5.
This article discusses the most interesting studies on functional and motor gastrointestinal disorders presented at Digestive Diseases Week (DDW), 2015. Researchers are still seeking biomarkers for irritable bowel syndrome and have presented new data. One study confirmed that the use of low-dose antidepressants has an antinociceptive effect without altering the psychological features of patients with functional dyspepsia. A contribution that could have immediate application is the use of transcutaneous electroacupuncture, which has demonstrated effectiveness in controlling nausea in patients with gastroparesis. New data have come to light on the importance of diet in irritable bowel syndrome, although the effectiveness of a low-FODMAP diet seems to be losing momentum with time. Multiple data were presented on the long-term efficacy of rifaximin therapy in patients with irritable bowel syndrome and diarrhoea. In addition, among other contributions, and more as a curiosity, a study evaluated the effect of histamine in the diet of patients with irritable bowel syndrome.
本文讨论了在2015年消化疾病周（DDW）上发表的关于功能性和运动性胃肠疾病的最有趣的研究。研究人员仍在寻找肠易激综合征的生物标志物，并公布了新的数据。一项研究证实，使用低剂量抗抑郁药具有抗伤害感受作用，且不会改变功能性消化不良患者的心理特征。经皮电针疗法的应用可能会立即产生效果，该疗法已证明在控制胃轻瘫患者的恶心方面有效。关于饮食在肠易激综合征中的重要性有了新的数据，尽管低发酵性寡糖、双糖、单糖和多元醇（FODMAP）饮食的有效性似乎随着时间的推移而减弱。关于利福昔明治疗肠易激综合征和腹泻患者的长期疗效有多项数据公布。此外，在其他研究成果中，更具趣味性的是，一项研究评估了组胺在肠易激综合征患者饮食中的作用。
