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有症状的早期先天性梅毒:一种常见却被遗忘的疾病。

Symptomatic Early Congenital Syphilis: A Common but Forgotten Disease.

作者信息

Rashid Usman, Yaqoob Usman, Bibi Nazia, Bari Attia

机构信息

Department of Pediatric Medicine, Children Hospital and Institute of Child Health, Lahore.

出版信息

J Coll Physicians Surg Pak. 2015 Oct;25 Suppl 2:S137-9. doi: 10.2015/JCPSP.S137S139.

DOI:10.2015/JCPSP.S137S139
PMID:26522203
Abstract

Congenital syphilis is a severe, disabling infection often with grave consequences seen in infants. It occurs due to the transmission of the disease from an infected mother to the unborn infant through the placenta. Congenital syphilis can involve any organ system and present with various symptoms. However, early diagnosis of congenital syphilis is difficult because more than half of the affected infants are asymptomatic, and the signs in symptomatic infants may be subtle and nonspecific. The continuing prevalence of this disease reveals the failure of control measures established for its prevention. Here we report a case of a one-month infant who presented with skin rash. The report stresses upon the importance of implementing the World Health Organization's recommendation that all pregnant women should be screened for syphilis in the first antenatal visit in the first trimester and again in the late pregnancy.

摘要

先天性梅毒是一种严重的、致残性感染,常见于婴儿,往往会造成严重后果。它是由于疾病通过胎盘从受感染的母亲传播给未出生的婴儿而发生的。先天性梅毒可累及任何器官系统,并表现出各种症状。然而,先天性梅毒的早期诊断很困难,因为超过一半的受影响婴儿没有症状,而有症状婴儿的体征可能很细微且不具特异性。这种疾病的持续流行表明为预防该病而制定的控制措施未能奏效。在此,我们报告一例出现皮疹的1个月大婴儿的病例。该报告强调了实施世界卫生组织建议的重要性,即所有孕妇应在孕早期的首次产前检查时以及妊娠晚期再次接受梅毒筛查。

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